Evidence map›Paper›PMID 36145992›Full record

ReviewPolymers2022

Preparation and Characteristics of Alginate Microparticles for Food, Pharmaceutical and Cosmetic Applications.

Anna Łętocha, Małgorzata Miastkowska, Elżbieta Sikora

Abstract readReview
In one paragraph

Review in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anna ŁętochaFaculty of Chemical Engineering and Technology, Institute of Organic Chemistry and Technology, Cracow University of Technology, 31-155 Krakow, Poland.
Małgorzata MiastkowskaFaculty of Chemical Engineering and Technology, Institute of Organic Chemistry and Technology, Cracow University of Technology, 31-155 Krakow, Poland.ORCID 0000-0002-4590-9184
Elżbieta SikoraFaculty of Chemical Engineering and Technology, Institute of Organic Chemistry and Technology, Cracow University of Technology, 31-155 Krakow, Poland.ORCID 0000-0003-4867-965X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alginates are the most widely used natural polymers in the pharmaceutical, food and cosmetic industries. Usually, they are applied as a thickening, gel-forming and stabilizing agent. Moreover, the alginate-based formulations such as matrices, membranes, nanospheres or microcapsules are often used as delivery systems. Alginate microparticles (AMP) are biocompatible, biodegradable and nontoxic carriers, applied to encapsulate hydrophilic active substances, including probiotics. Here, we report the methods most frequently used for AMP production and encapsulation of different actives. The technological parameters important in the process of AMP preparation, such as alginate concentration, the type and concentration of other reagents (cross-linking agents, oils, emulsifiers and pH regulators), agitation speed or cross-linking time, are reviewed. Furthermore, the advantages and disadvantages of alginate microparticles as delivery systems are discussed, and an overview of the active ingredients enclosed in the alginate carriers are presented.

Indexed as

active substancesalginateencapsulation techniquesmicroparticlesprobiotics

Identifiers

PMID36145992
PMCPMC9502979

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.