Evidence map›Paper›PMID 36146809›Full record

ReviewViruses2022

Porcine Circovirus Type 2 Vaccines: Commercial Application and Research Advances.

Jinshuo Guo, Lei Hou, Jianwei Zhou, Dedong Wang, Yongqiu Cui, Xufei Feng, Jue Liu

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Efficacy of a new ready-to-use PCV2 andVeterinarni medicina · 2025
    Article
  18. Article
  19. Article
  20. Speculative Review on the Feasibility of Porcine Circovirus 2 Elimination.Animals : an open access journal from MDPI · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jinshuo GuoDepartment of Preventive Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225012, China.
Lei HouDepartment of Preventive Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225012, China.
Jianwei ZhouDepartment of Preventive Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225012, China.
Dedong WangDepartment of Preventive Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225012, China.
Yongqiu CuiDepartment of Preventive Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225012, China.ORCID 0000-0003-3459-7047
Xufei FengDepartment of Preventive Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225012, China.
Jue LiuDepartment of Preventive Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225012, China.
Yangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine circovirus type 2 (PCV2) infection can lead to porcine circovirus-associated disease (PCVAD), causing great economic losses to the global swine industry. Conventional vaccination programs are a major measure in the prevention and control of this disease. Currently, there are 5 commercially available PCV2 vaccines in the international market and 10 kinds commercially available PCV2 vaccines in the Chinese market that confer good efficacy against this virus by alleviating clinicopathological manifestations and enhancing growth performance in pigs. In addition, diverse experimental PCV2 vaccines with protective efficiency have been developed, including attenuated chimeric, nucleic acid, subunit, multivalent, and viral-vectored vaccines. These experimental vaccines have been shown to be relatively effective in improving the efficiency of pig production and simplifying prevention procedures. Adjuvants can be used to promote vaccines with higher protective immunity. Herein, we review the application of multiple commercial vaccines over the years and research advances in experimental vaccines, which provide the possibility for the development of superior vaccines to successfully prevent and control PCV2 infection in the future.

Indexed as

Circoviridae InfectionsCircovirusNucleic AcidsSwine DiseasesViral VaccinesAnimalsAntibodies, ViralSwineAntibodies, ViralNucleic AcidsViral Vaccinesadjuvantcommercial vaccinesexperimental vaccinesPCV2PCVADprotective efficiency

Identifiers

PMID36146809
PMCPMC9504358
OpenAlexW4296764268

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.