ArticleTherapeutic advances in neurological disorders2022
Effect of early integrated robot-assisted gait training on motor and balance in patients with acute ischemic stroke: a single-blinded randomized controlled trial.
Article in Therapeutic advances in neurological disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 9 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Effectiveness of non-pharmacological interventions for lower limb motor impairment in post-stroke hemiplegia: a systematic review and Bayesian network meta-analysis.Journal of neuroengineering and rehabilitation · 2026Pooled it
- Post-stroke lower limb rehabilitation: a comparative study between exoskeleton robots and traditional gait training.Journal of neuroengineering and rehabilitation · 2026Pooled it
- Robot-assisted therapy following stroke: what effects on quality of life, cognitive and psychosocial outcomes? A systematic review.Journal of rehabilitation medicine · 2026Pooled it
- Electromechanical-assisted training for walking after stroke.The Cochrane database of systematic reviews · 2025Pooled it
- Physical rehabilitation approaches for the recovery of function and mobility following stroke.The Cochrane database of systematic reviews · 2025Pooled it
- Effect of robot-assisted training for lower limb rehabilitation on lower limb function in stroke patients: a systematic review and meta-analysis.Frontiers in human neuroscience · 2025Pooled it
- Efficacy of robot-assisted gait training on lower extremity function in subacute stroke patients: a systematic review and meta-analysis.Journal of neuroengineering and rehabilitation · 2024Pooled it
- How robot-assisted gait training affects gait ability, balance and kinematic parameters after stroke: a systematic review and meta-analysis.European journal of physical and rehabilitation medicine · 2024Pooled it
- Effect of robot-assisted gait training on improving cardiopulmonary function in stroke patients: a meta-analysis.Journal of neuroengineering and rehabilitation · 2024Pooled it
- Development and Upgrade of a Robot That Enables Three-Dimensional Trunk Motion and Lower Limb Exercise for Stroke Patients: A Pilot Clinical Investigation Including a User Feasibility Test.BioMed research international · 2026Trial
- Feasibility and outcomes of supplemental gait training by robotic and conventional means in acute stroke rehabilitation.Journal of neuroengineering and rehabilitation · 2023Trial
- Comparative Efficacy of Exercise Modalities for Motor Function Recovery After Acute Ischemic Stroke: A Systematic Review and Bayesian Network Meta-Analysis.Life (Basel, Switzerland) · 2026Review
- Development and Validation of a Clinical Model (SHACEA) for Post-stroke Cognitive Impairment Prognosis Occurred at Acute Phase and Last to 6 Months.Molecular neurobiology · 2025Article
- Rehabilitation training robot using mirror therapy for the upper and lower limb after stroke: a prospective cohort study.Journal of neuroengineering and rehabilitation · 2025Article
- Aerobic exercise, an effective intervention for cognitive impairment after ischemic stroke.Frontiers in aging neuroscience · 2025Review
- Robot-assisted gait training in stroke.Turkish journal of physical medicine and rehabilitation · 2024Review
- Article
- General Treatments Promoting Independent Living in Parkinson's Patients and Physical Therapy Approaches for Improving Gait-A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2024Review
- A Comprehensive Review: Robot-Assisted Treatments for Gait Rehabilitation in Stroke Patients.Medicina (Kaunas, Lithuania) · 2024Review
- Effects of Stroke Rehabilitation Using Gait Robot-Assisted Training and Person-Centered Goal Setting: A Single Blinded Pilot Study.Healthcare (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Gait disruption is a common poststroke problem. Robot-assisted gait training (RAGT) might improve motor function, balance, and activities of daily living. Objective: We compared the clinical effectiveness of early integrated RAGT using the Walkbot robotic gym with an intensity-matched enhanced lower limb therapy (ELLT) program and with conventional rehabilitation therapy (CRT) in patients with acute ischemic stroke. Methods: A total of 192 patients with acute ischemic stroke were randomly assigned (1:1:1) to receive RAGT, ELLT, or CRT. All three groups received 45 min of training daily, 3 days a week, for 4 weeks consecutively. Before and after the 4-week treatment, the patients were assessed based on a 6-minute walking test (6MWT), functional ambulation classification (FAC), timed up and go (TUG) test, dual-task walking (DTW) test, Tinetti's test, Barthel's index (BI), stroke-specific quality of life (SS-QOL) scale, and gait analysis parameters. Results: After the 4-week intervention, the results of the 6MWT, FAC, TUG, DTW, Tinetti's test, BI, SS-QOL, and gait in the three groups significantly improved. Compared with ELLT and CRT groups, participants in the RAGT group had a better performance in 6MWT (199.11 ± 60.72 Conclusion: In the acute stroke phase, early integrated RAGT showed greater performance in gait rehabilitation than CRT and ELLT. Registration: ChiCTR1900026225.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.