Evidence map›Paper›PMID 36154556›Full record

Observational studyRenal failure2022

A nomogram predicts cardiovascular events in patients with peritoneal dialysis-associated peritonitis.

Dan-Dan Huang, Yuan-Yuan Li, Xiang-Ming Qi, Yong-Gui Wu

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dan-Dan HuangDepartment of Nephropathy, the First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, PR China.
Yuan-Yuan LiDepartment of Nephropathy, the First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, PR China.
Xiang-Ming QiDepartment of Nephropathy, the First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, PR China.
Yong-Gui WuDepartment of Nephropathy, the First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, PR China.
First Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo predict the risk factors for cardiovascular events within 5 years in patients with peritoneal dialysis-associated peritonitis and establish a nomogram for clinical prediction.

methodsA prediction model was established by conducting an observational study in 150 patients with peritoneal dialysis-associated peritonitis obtained from the Information Database of AnHui Medical University Affiliated Hospital. The nomogram was constructed using the multivariate COX regression model. The C-index and the calibration plot were used to assess the discrimination and calibration of the prediction model.

resultsThe elderly [HR = 2.453 (1.071-5.619)], history of cardiovascular events [HR = 2.296 (1.220-4.321)], alkaline phosphatase [HR = 1.004 (1.002-1.005)] and culture-positive [HR= 2.173 (1.009-4.682)] were identified as risk predictors of cardiovascular events, while serum albumin [HR = 0.396(0.170-0.924)] was identified as protective predictors of cardiovascular events. Combined with clinical studies, we constructed a nomogram based on the minimum value of the Akaike Information Criterion or Bayesian Information Criterion. The C index of the nomogram is 0.732, revealing great discrimination and appropriate calibration. Through the total score of the nomogram and the result of ROC, we classify patients into high-risk groups (cardiovascular events group) and low-risk groups (no cardiovascular events group). Cardiovascular events were significantly different for patients in the high-risk group compared to the low-risk group (HR = 3.862(2.202-6.772;

conclusionsThe current novel nomogram can accurately predict cardiovascular events in patients with peritonitis associated with peritoneal dialysis. However, external validation is required before the model can be used in clinic settings.

Indexed as

Peritoneal DialysisPeritonitisAgedAlkaline PhosphataseBayes TheoremHumansNomogramsRetrospective StudiesSerum AlbuminAlkaline PhosphataseSerum Albumincardiovascular eventsnomogramPeritoneal dialysis-related peritonitisrisk factors

Identifiers

PMID36154556
PMCPMC9518274
OpenAlexW4297239253

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.