Evidence mapPaperPMID 36157208Full record

Trial reportDisease markers2022

Laparoscopic Radical Hysterectomy Combined with Neoadjuvant Chemotherapy for Cervical Cancer Patients Effectively Improves Immune Function.

Mo Liu, Hongping Wang, Shengye Du, Wenying Li, Fei Xuan, Yinghui Zhao, Na Li

RetractedAbstract readRandomized Controlled TrialRetracted Publication
In one paragraph

Trial report in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Mo LiuDepartment of Gynecology and Obstetrics, People's Hospital Affiliated to Shandong First Medical University, Jinan 271199, Shandong Province, China.
Hongping WangDepartment of Gynecology and Obstetrics, People's Hospital Affiliated to Shandong First Medical University, Jinan 271199, Shandong Province, China.
Shengye DuDepartment of Gynecology and Obstetrics, People's Hospital Affiliated to Shandong First Medical University, Jinan 271199, Shandong Province, China.
Wenying LiDepartment of Gynecology and Obstetrics, People's Hospital Affiliated to Shandong First Medical University, Jinan 271199, Shandong Province, China.
Fei XuanDepartment of Oncology, People's Hospital Affiliated to Shandong First Medical University, Jinan 271199, Shandong Province, China.ORCID https://orcid.org/0000-0003-2943-3961
Yinghui ZhaoDepartment of Gynecology and Obstetrics, People's Hospital Affiliated to Shandong First Medical University, Jinan 271199, Shandong Province, China.
Na LiDepartment of Chinese Medicine Gynecology, People's Hospital Affiliated to Shandong First Medical University, Jinan 271199, Shandong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the clinical efficacy of neoadjuvant chemotherapy plus laparoscopic radical hysterectomy for cervical cancer and the effect on the immune function of patients. Methods: Between January 2021 and December 2021, 42 patients with cervical cancer diagnosed and treated at our hospital were recruited and randomly assigned at a 1 : 1 ratio to receive neoadjuvant chemotherapy plus open radical hysterectomy (control group) or neoadjuvant chemotherapy plus laparoscopic radical hysterectomy (treatment group) (study group). Outcome measures included surgical indices, clinical outcomes, and immunological function. Results: There were no significant differences in the operative time between the two groups ( Conclusion: Neoadjuvant chemotherapy plus laparoscopic radical hysterectomy effectively improves clinical efficacy, lowers cancer marker levels, improves patients' immune function, reduces the risk of adverse events, and improves patients' prognosis with less intraoperative bleeding, less trauma, faster postoperative recovery, and shorter hospital stay for cervical cancer patients.

Indexed as

HysterectomyLaparoscopyUterine Cervical NeoplasmsCarcinoembryonic AntigenFemaleHumansImmunityNeoadjuvant TherapyNeoplasm StagingRetrospective StudiesCarcinoembryonic Antigen

Identifiers

PMID36157208
PMCPMC9492327

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.