Evidence map›Paper›PMID 36159456›Full record

ReviewFrontiers in nutrition2022

Personalized nutrition: A review of genotype-based nutritional supplementation.

Feijie Wang, Jianheng Zheng, Junrui Cheng, Hong Zou, Mingfeng Li, Bin Deng, Rong Luo, Feng Wang, Dingqiang Huang, Gang Li and 6 more

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Targeted nutritional strategies in postoperative care.Anesthesia and pain medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Feijie WangNutrilite Health Institute, Shanghai, China.
Jianheng ZhengNutrilite Health Institute, Shanghai, China.
Junrui ChengDepartment of Molecular and Structural Biochemistry, North Carolina State University, Kannapolis, NC, United States.
Hong ZouSequanta Technologies Co., Ltd, Shanghai, China.
Mingfeng LiNutrilite Health Institute, Shanghai, China.
Bin DengNutrilite Health Institute, Guangzhou, China.
Rong LuoNutrilite Health Institute, Guangzhou, China.
Feng WangNutrilite Health Institute, Guangzhou, China.
Dingqiang HuangNutrilite Health Institute, Guangzhou, China.
Gang LiNutrilite Health Institute, Shanghai, China.
Rao ZhangSchool of Public Health, Institute of Nutrition and Health, Qingdao University, Qingdao, China.
Xin DingSchool of Public Health, Institute of Nutrition and Health, Qingdao University, Qingdao, China.
Yuan LiSequanta Technologies Co., Ltd, Shanghai, China.
Jun DuNutrilite Health Institute, Shanghai, China.
Yuexin YangChinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Beijing, China.
Juntao KanNutrilite Health Institute, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutritional disorders have become a major public health issue, requiring increased targeted approaches. Personalized nutrition adapted to individual needs has garnered dramatic attention as an effective way to improve nutritional balance and maintain health. With the rapidly evolving fields of genomics and nutrigenetics, accumulation of genetic variants has been indicated to alter the effects of nutritional supplementation, suggesting its indispensable role in the genotype-based personalized nutrition. Additionally, the metabolism of nutrients, such as lipids, especially omega-3 polyunsaturated fatty acids, glucose, vitamin A, folic acid, vitamin D, iron, and calcium could be effectively improved with related genetic variants. This review focuses on existing literatures linking critical genetic variants to the nutrient and the ways in which these variants influence the outcomes of certain nutritional supplementations. Although further studies are required in this direction, such evidence provides valuable insights for the guidance of appropriate interventions using genetic information, thus paving the way for the smooth transition of conventional generic approach to genotype-based personalized nutrition.

Indexed as

genotypenutrientnutrigeneticsnutritional supplementationpersonalized nutritionsingle nucleotide polymorphisms

Identifiers

PMID36159456
PMCPMC9500586

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.