Evidence map›Paper›PMID 36160241›Full record

ReviewFrontiers in microbiology2022

Variability of murine bacterial pneumonia models used to evaluate antimicrobial agents.

Rakel Arrazuria, Bernhard Kerscher, Karen E Huber, Jennifer L Hoover, Carina Vingsbo Lundberg, Jon Ulf Hansen, Sylvie Sordello, Stephane Renard, Vincent Aranzana-Climent, Diarmaid Hughes and 3 more

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Bridging bench and bedside: translational omics ofEuropean respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Article
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Nanomaterials (Basel, Switzerland) · 2025
    Review
  12. Recent advances in host models in studying virulence factors and pathogenesis ofFrontiers in cellular and infection microbiology · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rakel ArrazuriaDivision of Microbiology, Paul-Ehrlich-Institut, Langen, Germany.
Bernhard KerscherDivision of Microbiology, Paul-Ehrlich-Institut, Langen, Germany.
Karen E HuberDivision of Microbiology, Paul-Ehrlich-Institut, Langen, Germany.
Jennifer L HooverInfectious Diseases Research Unit, GlaxoSmithKline Pharmaceuticals, Collegeville, PA, United States.
Carina Vingsbo LundbergDepartment of Bacteria, Parasites & Fungi, Statens Serum Institut, Copenhagen, Denmark.
Jon Ulf HansenDepartment of Bacteria, Parasites & Fungi, Statens Serum Institut, Copenhagen, Denmark.
Sylvie SordelloInfectious Diseases, Evotec, Toulouse, France.
Stephane RenardInfectious Diseases, Evotec, Toulouse, France.
Vincent Aranzana-ClimentDepartment of Pharmacy, Uppsala University, Uppsala, Sweden.
Diarmaid HughesDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Philip GribbonFraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, Hamburg, Germany.
Lena E FribergDepartment of Pharmacy, Uppsala University, Uppsala, Sweden.
Isabelle Bekeredjian-DingDivision of Microbiology, Paul-Ehrlich-Institut, Langen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance has become one of the greatest threats to human health, and new antibacterial treatments are urgently needed. As a tool to develop novel therapies, animal models are essential to bridge the gap between preclinical and clinical research. However, despite common usage of

Indexed as

antimicrobialantimicrobial efficacy studiesGram-negativelung infectionmurine pneumonia modelPK/PD

Identifiers

PMID36160241
PMCPMC9493352

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.