Evidence map›Paper›PMID 36160381›Full record

ArticleFrontiers in pharmacology2022

Dysregulation of dopamine neurotransmission in the nucleus accumbens in immobilization-induced hypersensitivity.

Yuki Kishikawa, Yukie Kawahara, Yoshinori N Ohnishi, Naoki Sotogaku, Tomoko Koeda, Hiroshi Kawahara, Akinori Nishi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuki KishikawaDepartment of Rehabilitation Sciences, Faculty of Rehabilitation Sciences, Nishikyushu University, Kanzaki, Japan.
Yukie KawaharaDepartment of Pharmacology, Kurume University School of Medicine, Kurume, Japan.
Yoshinori N OhnishiDepartment of Pharmacology, Kurume University School of Medicine, Kurume, Japan.
Naoki SotogakuDepartment of Pharmacology, Kurume University School of Medicine, Kurume, Japan.
Tomoko KoedaDepartment of Physical Therapy, Faculty of Rehabilitation Sciences, Nagoya Gakuin University, Nagoya, Japan.
Hiroshi KawaharaDepartment of Dental Anesthesiology, Tsurumi University School of Dental Medicine, Yokohama, Japan.
Akinori NishiDepartment of Pharmacology, Kurume University School of Medicine, Kurume, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cast immobilization causes sensory hypersensitivity, which is also a symptom of neuropathic pain and chronic pain. However, the mechanisms underlying immobilization-induced hypersensitivity remain unclear. The present study investigated the role of dopamine neurotransmission in the nucleus accumbens shell (NAcSh) of rats with cast immobilization-induced mechanical hypersensitivity using

Indexed as

D2-like receptorhyperalgesiamicrodialysispostsynapticrat

Identifiers

PMID36160381
PMCPMC9493457

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.