Evidence map›Paper›PMID 36161997›Full record

ReviewCureus2022

Gut Microbiota Interventions for the Management of Obesity: A Literature Review.

Vikram Jeet Singh Gill, Suha Soni, Manasi Shringarpure, Anusheel, Sushant Bhardwaj, Narendra Kumar Yadav, Ankit Patel, Avaniben Patel

Registry-linked trialAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06030999 (Three Arms, Randomized, Double-blind Controlled Trial Of Prevention And Treatment On Obesity And Weight Management By Oral Supplementation Of Probiotics And Prebiotics), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06030999 nacompletednot on this mapstarted 2023, after this paper: background citation

Three Arms, Randomized, Double-blind Controlled Trial Of Prevention And Treatment On Obesity And Weight Management By Oral Supplementation Of Probiotics And Prebiotics

TypeinterventionalSponsorShenzhen Precision Health Food Technology Co. Ltd.,Ran2023 to 2023Enrolled150ConditionsOverweight and ObesityArmsStudy product A (Wonderlab wonder4shape), Study product B (Wonderlab wonder4shape), Study product C (placebo)
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. The gut microbiota in malnutrition.Nature reviews. Microbiology · 2026
    Review
  4. Review
  5. Intestinal-related substances in obesity regulation: A comprehensive review.World journal of gastrointestinal pharmacology and therapeutics · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. A comprehensive review of genetic causes of obesity.World journal of pediatrics : WJP · 2024
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vikram Jeet Singh GillInternal Medicine, Baylor College of Medicine, Houston, USA.
Suha SoniMedicine, Punjab Institute of Medical Sciences, Jalandhar, IND.
Manasi ShringarpureMedicine, The Institute of Liver and Biliary Sciences (ILBS), Delhi, IND.
AnusheelGeneral Practice, Shanti Gopal Hospital, Ghaziabad, IND.
Sushant BhardwajMedicine, Kathmandu University School of Medical Sciences, Kathmandu, NPL.
Narendra Kumar YadavMedicine, Nepalgunj Medical College, Kathmandu, NPL.
Ankit PatelInternal Medicine, Spartan Health Science University School of Medicine, Vieux Fort, LCA.
Avaniben PatelInternal Medicine, Spartan Health Science University School of Medicine, Vieux Fort, LCA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota (GM) has been recognized as an important factor in the development of metabolic diseases such as obesity; it has been reported that the composition of the GM differs in obese and lean subjects, suggesting that microbiota dysbiosis can contribute to changes in body weight. Dysbiosis occurs due to an imbalance in the composition of gut bacteria, changes in the metabolic process, or changes in the distribution of microbiota within the gut. Dysbiosis can change the functioning of the intestinal barrier and the gut-associated lymphoid tissues (GALT). Microbial manipulation may help with preventing or treating weight gain and associated comorbidities. Approaches to this may range from dietary manipulation, which is suitable to treat the individual's microflora, to probiotics, prebiotics, synbiotics, and fecal microbiota transplant (FMT).

Indexed as

dysbiosisgutgut microbiomegut microbiotaintestinal microbiotametabolismmicrobiotaobesityprobiotics and microbiomescfa

Identifiers

PMID36161997
PMCPMC9484223

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.