Evidence map›Paper›PMID 36163166›Full record

ArticleJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2023

Clinical outcomes of adults and children with cystic fibrosis during the COVID-19 pandemic.

Michael Doumit, Sandra Chuang, Peter Middleton, Hiran Selvadurai, Sheila Sivam, Rasa Ruseckaite, Susannah Ahern, Kylie Ann Mallitt, Verity Pacey, Kelly Gray and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  10. A year in review (2022): Modulators and COVID19, the story goes on….Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Michael DoumitDepartment of Health Sciences, Macquarie University, Department of Health Sciences, 75 Talavera Rd, Macquarie University, Macquarie Park, NSW 2109, Australia; School of Women's and Children's Health, University of New South Wales, Address Level 8, Bright Alliance Building, High St, Randwick, NSW, Australia. Electronic address: Michael.Doumit@mq.edu.au.
Sandra ChuangSchool of Women's and Children's Health, University of New South Wales, Address Level 8, Bright Alliance Building, High St, Randwick, NSW, Australia; Respiratory Medicine Department, Sydney Children's Hospital, Level 0, South West Wing, Sydney Children's Hospital, High St, Randwick, NSW, Australia.
Peter MiddletonRespiratory Medicine Department, Westmead Hospital, Level 2, Clinical Sciences Building, PO Box 533, Westmead Hospital, Westmead, Australia.
Hiran SelvaduraiRespiratory Medicine Department, The Children's Hospital at Westmead, Corner or Hawkesbury Rd and Hainsworth St, Locked Bag 4001, Westmead, Australia.
Sheila SivamThe Department of Respiratory Medicine, Royal Prince Alfred Hospital, Level 11, Building 75, RPA Hospital Missenden Rd, Camperdown, Australia.
Rasa RuseckaiteDepartment of Public Health and Preventive Medicine, Monash University, Level 3, 553 St Kilda Rd, Melbourne, Australia.
Susannah AhernDepartment of Epidemiology and Preventive Medicine, Monash University, Level 3, 553 St Kilda Rd, Melbourne, Australia.
Kylie Ann MallittSydney School of Public Health, University of Sydney, Edward Ford Building A27, The University of Sydney, NSW, Australia. Department of Health Sciences, Macquarie University, Macquarie Park, Australia.
Verity PaceyDepartment of Health Sciences, Macquarie University, Department of Health Sciences, 75 Talavera Rd, Macquarie University, Macquarie Park, NSW 2109, Australia.
Kelly GrayDepartment of Health Sciences, Macquarie University, Department of Health Sciences, 75 Talavera Rd, Macquarie University, Macquarie Park, NSW 2109, Australia.
Adam JaffeSchool of Women's and Children's Health, University of New South Wales, Address Level 8, Bright Alliance Building, High St, Randwick, NSW, Australia; Respiratory Medicine Department, Sydney Children's Hospital, Level 0, South West Wing, Sydney Children's Hospital, High St, Randwick, NSW, Australia.
UNSW Sydney · AUMacquarie University · AUMonash University · AUChildren's Hospital at Westmead · AURoyal Prince Alfred Hospital · AUThe University of Sydney · AUWestmead Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe onset of the COVID-19 pandemic was associated with restricted community movement and limited access to healthcare facilities, resulting in changed clinical service delivery to people with cystic fibrosis (CF). This study aimed to determine clinical outcomes of Australian adults and children with CF in the 12-months following the onset of the COVID-19 pandemic.

methodsThis longitudinal cohort study used national registry data. Primary outcomes were 12-month change in percent predicted forced expiratory volume in one second (FEV1 %pred), body mass index (BMI) in adults and BMI z-scores in children. A piecewise linear mixed-effects model was used to determine trends in outcomes before and after pandemic onset.

resultsData were available for 3662 individuals (median age 19.6 years, range 0-82). When trends in outcomes before and after pandemic onset were compared; FEV1 %pred went from a mean annual decline of -0.13% (95%CI -0.36 to 0.11) to a mean improvement of 1.76% (95%CI 1.46-2.05). Annual trend in BMI improved from 0.03 kg/m

conclusionIn the 12-months following the onset of the COVID-19 pandemic, there was an improvement in the clinical outcomes of people with CF when compared to the pre-pandemic period.

Indexed as

COVID-19Cystic FibrosisAdolescentAdultAgedAged, 80 and overAustraliaChildChild, PreschoolForced Expiratory VolumeHumansInfantInfant, NewbornLongitudinal StudiesMiddle AgedPandemicsCOVID-19Cystic fibrosisTelehealth

Identifiers

PMID36163166
PMCPMC9477965
OpenAlexW4296198687

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.