ArticleImmunity & ageing : I & A2022
The reference ranges and characteristics of lymphocyte parameters and the correlation between lymphocyte parameters and routine health indicators in adults from China.
Article in Immunity & ageing : I & A, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Using Immune Clusters for Classifying Heterogeneity of Immunity in Healthy Adults.Current medical science · 2026Article
- Antibody landscapes of arboviral exposure across China revealed by high-throughput seroprofiling from a peptide epitope library.Infectious diseases of poverty · 2026Article
- A context-aware interpretive framework for lymphocyte immunophenotyping by flow cytometry.Frontiers in immunology · 2026Article
- Prediction of postoperative infection through early-stage salivary microbiota following kidney transplantation using machine learning techniques.Renal failure · 2025Article
- Immune biomarkers for predicting postoperative pneumonia following hip fracture surgery.Biomarkers in medicine · 2025Article
- Immunosenescence and interactions for lymphocyte deep immunophenotyping.Journal of translational medicine · 2025Article
- Age-dependent immune profile in healthy individuals: an original study, systematic review and meta-analysis.Immunity & ageing : I & A · 2024Article
- Remodeling the tumor-immune microenvironment by anti-CTLA4 blockade enhanced subsequent anti-PD-1 efficacy in advanced nasopharyngeal carcinoma.NPJ precision oncology · 2024Article
Corrections and comments
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Authors and funding
21 authors.
Funding
Abstract
backgroundAssessment of immune function is of key importance in recognition of disease or healthy status, which still faces challenge in clinical practice. We conducted a 10-center study to investigate lymphocyte parameters including the number, phenotype and IFN-γ-producing ability, and routine laboratory indicators by using the standard method.
resultsAlthough the heterogeneity of lymphocyte parameters was widely found, we have established the normal ranges of these parameters by using pooled data which showed no significant difference among centers. Cluster analysis of 35 parameters found 3 interesting clusters which represented different immunological status. Cluster 1 (parameters: IFN-γ
conclusionsWe have established the normal ranges of lymphocyte parameters in different areas. This study elucidates the key indicators used to reflect the current function or potential of lymphocytes, which may provide a valuable clue for how to keep immunity healthy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.