Evidence map›Paper›PMID 36173237›Full record

Trial reportDiabetes technology & therapeutics2022

Positive Impact of the Bionic Pancreas on Diabetes Control in Youth 6-17 Years Old with Type 1 Diabetes: A Multicenter Randomized Trial.

Laurel H Messer, Bruce A Buckingham, Fran Cogen, Mark Daniels, Greg Forlenza, Rabab Z Jafri, Nelly Mauras, Andrew Muir, R Paul Wadwa, Perrin C White and 9 more

Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Diabetes technology & therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04200313 (The Insulin-Only Bionic Pancreas Pivotal Trial), which is not on this map. Cited by 33 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 7 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04200313 nacompletednot on this map

The Insulin-Only Bionic Pancreas Pivotal Trial: Testing the iLet in Adults and Children With Type 1 Diabetes

TypeinterventionalSponsorJaeb Center for Health ResearchRan2020 to 2022Enrolled440ConditionsDiabetes Mellitus, Type 1 Diabetes, Diabetes Mellitus, Type 1ArmsBionic Pancreas (BP) with Aspart or Lispro, Bionic Pancreas with Fiasp (BPFiasp), Usual Care (UC), BP Guidance Insulin Dosing
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 7 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Real-World Evidence of Automated Insulin Delivery System Use.Diabetes technology & therapeutics · 2024
    Pooled it
  6. Guideline
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Early Stages of Automated Insulin Delivery.Diabetes technology & therapeutics · 2025
    Review
  18. Early Stages of Automated Insulin Delivery.Journal of diabetes science and technology · 2025
    Review
  19. Registration and Real-Life Studies on Automated Insulin Delivery Systems.Journal of diabetes science and technology · 2025
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 11 institutions in 1 country.

Laurel H MesserBarbara Davis Center for Diabetes, University of Colorado, Aurora, Colorado, USA.ORCID 0000-0001-7493-0989
Bruce A BuckinghamDepartment of Pediatrics, Division of Pediatric Endocrinology and Diabetes, Stanford University School of Medicine, Palo Alto, California, USA.
Fran CogenDepartment of Endocrinology and Diabetes, Children's National Medical Center, Washington, District of Columbia, USA.
Mark DanielsEndocrinology and Diabetes Division, Children's Hospital of Orange County, Orange, California, USA.
Greg ForlenzaBarbara Davis Center for Diabetes, University of Colorado, Aurora, Colorado, USA.ORCID 0000-0003-3607-9788
Rabab Z JafriDivision of Pediatric Endocrinology and Diabetes, University of Texas Health Science Center, San Antonio, San Antonio, Texas, USA.
Nelly MaurasDivision of Endocrinology, Diabetes & Metabolism, Department of Pediatrics, Nemours Children's Health System, Jacksonville, Florida, USA.
Andrew MuirDepartment of Pediatrics, Emory University, Atlanta, Georgia, USA.
R Paul WadwaBarbara Davis Center for Diabetes, University of Colorado, Aurora, Colorado, USA.ORCID 0000-0002-4139-2122
Perrin C WhiteDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Steven J RussellDiabetes Research Center, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-8423-5891
Edward R DamianoDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts, USA.
Firas H El-KhatibDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts, USA.
Katrina J RuedyJAEB Center for Health Research, Tampa, Florida, USA.
Courtney A BalliroDiabetes Research Center, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Zoey LiJAEB Center for Health Research, Tampa, Florida, USA.
Martin Chase MarakJAEB Center for Health Research, Tampa, Florida, USA.
Peter CalhounJAEB Center for Health Research, Tampa, Florida, USA.ORCID 0000-0002-5325-7200
Roy W BeckJAEB Center for Health Research, Tampa, Florida, USA.ORCID 0000-0002-5194-8446
Jaeb Center for Health Research · USUniversity of Colorado Anschutz Medical Campus · USBoston University · USMassachusetts General Hospital · USChildren's Hospital of Orange County · USChildren's National · USEmory University · USNemours Children's Health System · USPalo Alto University · USThe University of Texas Health Science Center at San Antonio · USThe University of Texas Southwestern Medical Center · US

Funding

NIDDK NIH HHS UC4 DK108612
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 1HypoglycemiaAdolescentBionicsBlood GlucoseBlood Glucose Self-MonitoringChildGlycated HemoglobinHumansHypoglycemic AgentsInsulinInsulin AspartInsulin Infusion SystemsInsulin LisproInsulin, Regular, HumanPancreasBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulinInsulin AspartInsulin LisproInsulin, Regular, HumanArtificial pancreasAutomated insulin deliveryBionic pancreasEvaluationPediatricsType 1 diabetes

Identifiers

PMID36173237
PMCPMC9529304
OpenAlexW4298013220

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.