Evidence map›Paper›PMID 36173697›Full record

ReviewAnnual review of virology2022

Replication Compartments of Eukaryotic and Bacterial DNA Viruses: Common Themes Between Different Domains of Host Cells.

David M Knipe, Amy Prichard, Surendra Sharma, Joe Pogliano

Open access · hybridAbstract readReview
In one paragraph

Review in Annual review of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. The biology of jumbo phages.Nature communications · 2026
    Review
  4. Review
  5. Viral interference of nucleocytoplasmic transport.The Journal of biological chemistry · 2025
    Review
  6. The Biology of Nucleus-Forming Jumbo Phages.Annual review of genetics · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. A transcriptionally active lipid vesicle encloses the injectedbioRxiv : the preprint server for biology · 2024
    Article
  12. Review
  13. Asesino: a nucleus-forming phage that lacks PhuZ.bioRxiv : the preprint server for biology · 2024
    Article
  14. Article
  15. An essential and highly selective protein import pathway encoded by nucleus-forming phage.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. International journal of molecular sciences · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

David M KnipeDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, USA; email: david_knipe@hms.harvard.edu.
Amy PrichardDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA; email: jpogliano@ucsd.edu.
Surendra SharmaDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, USA; email: david_knipe@hms.harvard.edu.
Joe PoglianoDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA; email: jpogliano@ucsd.edu.
Harvard University · USUniversity of California, San Diego · US

Funding

VIral and host mechanisms that tilt the HSV lytic/latent balanceP01AI098681 · NIAID · HARVARD MEDICAL SCHOOL · PI KNIPE, DAVID M. · 2013 to 2023
$19.2M
Molecular and cellular biology of the phage nucleus and spindleR01GM129245 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI POGLIANO, JOSEPH A · 2018 to 2025
$4.2M
Nuclear Sensing of Herpesviral DNAR01AI106934 · NIAID · HARVARD MEDICAL SCHOOL · PI KNIPE, DAVID M. · 2014 to 2021
$3.8M
Nuclear Sensing of Herpesviral DNAR56AI106934 · NIAID · HARVARD MEDICAL SCHOOL · PI KNIPE, DAVID M. · 2024 to 2024
$587k
NIAID NIH HHS P01 AI098681NIAID NIH HHS R01 AI106934NIAID NIH HHS R56 AI106934NIGMS NIH HHS R01 GM129245
6 · The paper itself

Abstract

Subcellular organization is essential for life. Cells organize their functions into organelles to concentrate their machinery and supplies for optimal efficiency. Likewise, viruses organize their replication machinery into compartments or factories within their host cells for optimal replicative efficiency. In this review, we discuss how DNA viruses that infect both eukaryotic cells and bacteria assemble replication compartments for synthesis of progeny viral DNA and transcription of the viral genome. Eukaryotic DNA viruses assemble replication compartments in the nucleus of the host cell while DNA bacteriophages assemble compartments called phage nuclei in the bacterial cytoplasm. Thus, DNA viruses infecting host cells from different domains of life share common replication strategies.

Indexed as

BacteriophagesVirusesBacteriaCell NucleusDNA, BacterialDNA, ViralDNA VirusesEukaryotaEukaryotic CellsVirus ReplicationDNA, BacterialDNA, ViralbacteriophageDNA virusinfectionphage nucleusviral replication compartment

Identifiers

PMID36173697
PMCPMC10311714
OpenAlexW4297932628

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.