Evidence map›Paper›PMID 36174571›Full record

ReviewNeuron2022

Bioelectronic medicine: Preclinical insights and clinical advances.

Valentin A Pavlov, Kevin J Tracey

Abstract readReview
In one paragraph

Review in Neuron, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Neuro-tumor interactions in peripheral tumors.Cancer metastasis reviews · 2026
    Review
  9. Review
  10. Soft electroceutical immunomodulation.National science review · 2026
    Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Valentin A PavlovInstitute of Bioelectronic Medicine, the Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA; Elmezzi Graduate School of Molecular Medicine, Northwell Health, Manhasset, NY, USA; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA. Electronic address: vpavlov@northwell.edu.
Kevin J TraceyInstitute of Bioelectronic Medicine, the Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA; Elmezzi Graduate School of Molecular Medicine, Northwell Health, Manhasset, NY, USA; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA. Electronic address: kjtracey@northwell.edu.

Funding

Molecular Basis of Bioelectronic MedicineR35GM118182 · NIGMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI TRACEY, KEVIN J · 2016 to 2025
$7.3M
Brainstem Cholinergic Circuitries in the Inflammatory Reflex during SepsisR01GM128008 · NIGMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI PAVLOV, VALENTIN ATANASSOV · 2018 to 2022
$1.8M
Orexinergic Modulation of Experimental SepsisR01GM121102 · NIGMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI DEUTSCHMAN, CLIFFORD SCOTT, PAVLOV, VALENTIN ATANASSOV · 2017 to 2020
$1.6M
Central cholinergic regulation of inflammationR01GM089807 · NIGMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI PAVLOV, VALENTIN ATANASSOV · 2011 to 2014
$1.1M
NIGMS NIH HHS R01 GM089807NIGMS NIH HHS R01 GM121102NIGMS NIH HHS R01 GM128008NIGMS NIH HHS R35 GM118182
6 · The paper itself

Abstract

The nervous system maintains homeostasis and health. Homeostatic disruptions underlying the pathobiology of many diseases can be controlled by bioelectronic devices targeting CNS and peripheral neural circuits. New insights into the regulatory functions of the nervous system and technological developments in bioelectronics drive progress in the emerging field of bioelectronic medicine. Here, we provide an overview of key aspects of preclinical research, translation, and clinical advances in bioelectronic medicine.

Identifiers

PMID36174571
PMCPMC10155266

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.