Evidence map›Paper›PMID 36174590›Full record

ArticleAmerican journal of perinatology2024

Heart Rate and Pulse Oximetry Dynamics in the First Week after Birth in Neonatal Intensive Care Unit Patients and the Risk of Cerebral Palsy.

Lisa Letzkus, Karen Fairchild, Genevieve Lyons, Harshini Pyata, Sarah Ratcliffe, Doug Lake

Open access · greenAbstract read
In one paragraph

Article in American journal of perinatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lisa LetzkusDepartment of Pediatrics, Neurodevelopmental and Behavioral Pediatrics, University of Virginia Children's, University of Virginia School of Medicine, Charlottesville, Virginia.ORCID 0000-0003-3309-7753
Karen FairchildDepartment of Pediatrics, Neonatology, University of Virginia Children's, University of Virginia School of Medicine, Charlottesville, Virginia.
Genevieve LyonsDepartment of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, Virginia.
Harshini PyataDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Sarah RatcliffeDepartment of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, Virginia.
Doug LakeDepartment of Cardiovascular Medicine, University of Virginia School of Medicine, Charlottesville, Virginia.
University of Virginia · USUniversity of Virginia Children's Hospital · USUniversity of North Carolina at Chapel Hill · US

Funding

The integrated Translational Health Research Institute of Virginia (iTHRIV): Using Data to Improve HealthUL1TR003015 · NCATS · UNIVERSITY OF VIRGINIA · PI BROWN, DONALD E, JOHNSTON, KAREN C. · 2019 to 2023
$20.3M
Institutional Career Development CoreKL2TR003016 · NCATS · UNIVERSITY OF VIRGINIA · PI PAPIN, JASON, WORRALL, BRADFORD B · 2019 to 2023
$3.9M
NCATS NIH HHS KL2 TR003016NCATS NIH HHS UL1 TR003015
6 · The paper itself

Abstract

objectiveInfants in the neonatal intensive care unit (NICU) are at high risk of adverse neuromotor outcomes. Atypical patterns of heart rate (HR) and pulse oximetry (SpO STUDY

designThis was a retrospective study including patients admitted to a level IV NICU from 2009 to 2017 with archived cardiorespiratory data in the first 7 days from birth to follow-up at >2 years of age. The mean, standard deviation (SD), skewness, kurtosis and cross-correlation of HR and SpO

resultsSeventy infants with CP and 1,733 controls met inclusion criteria for a 3.8% population prevalence. Area under the receiver operating characteristic curve for CP prediction was 0.7524 for the clinical model, 0.7419 for the vital sign model, and 0.7725 for the combined model. Variables included in the combined model were lower maternal age, outborn delivery, lower 5-minute Apgar's score, lower SD of HR, and more negative skewness of HR.

conclusionIn this study including NICU patients of all gestational ages, HR but not SpO KEY POINTS: · SD and skewness of HR have some added predictive value of later diagnosis of CP.. · SpO2 measures do not add to CP prediction.. · Combining clinical variables with early HR measures may improve the prediction of later CP..

Indexed as

Cerebral PalsyHeart RateIntensive Care Units, NeonatalOximetryFemaleHumansInfantInfant, NewbornInfant, PrematureMaleRetrospective StudiesRisk AssessmentROC Curve

Identifiers

PMID36174590
PMCPMC10050229
OpenAlexW4297989401

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.