Evidence mapPaperPMID 36175102Full record

ArticleBMJ open2022

Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for type 2 diabetes remission (ORDER): protocol of a multicentre, randomised controlled, open-label, superiority trial.

Mengyi Li, Yang Liu, Wei-Jei Lee, Scott A Shikora, Maud Robert, Weu Wang, Simon Kin Hung Wong, Yuanyuan Kong, Daniel King Hung Tong, Chun Hai Tan and 14 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05015283 (Efficacy and Safety of One-anastomosis Versus Roux-en-Y Gastric Bypass for Type 2 Diabetes Remission), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05015283 narecruitingnot on this map

Efficacy and Safety of One-anastomosis Versus Roux-en-Y Gastric Bypass for Type 2 Diabetes Remission (ORDER): a Multi-centric, Randomized, Open-label, Superiority Trial

TypeinterventionalSponsorBeijing Friendship HospitalRan2022 to 2026Enrolled248ConditionsType2 Diabetes, Complication of Bariatric ProcedureArmsThe laparoscopic One-anastomosis gastric bypass will consist of:, The laparoscopic Roux-en-Y gastric bypass will consist of:
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Mengyi Li *Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yang Liu *Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Wei-Jei LeeDepartment of Surgery, Min-Sheng General Hospital, Taiwan, China.
Scott A ShikoraDepartment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Maud RobertDepartment of Digestive and Bariatric Surgery, Hôpital Edouard Herriot, Lyon, France.
Weu WangDepartment of Surgery, Taipei Medical University Hospital, Taiwan, China.
Simon Kin Hung WongDepartment of Surgery, Prince of Wales Hospital, Hong Kong SAR, China.
Yuanyuan KongClinical Epidemiology & EBM Unit, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-2586-1443
Daniel King Hung TongSurgery Center, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Chun Hai TanSurgicare Bariatric and General Surgery Clinic, Singapore.
Na ZengSchool of Public Health, Peking University, Beijing, China.
Shaihong ZhuDepartment of General Surgery, The Third Xiangya Hospital of Central South University, Hunan, China.
Cunchuan WangDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Jinan University, Guangdong, China.
Pin ZhangDivision of Bariatric and Metabolic Surgery, Department of General Surgery, Shanghai Jiao Tong University affiliated Sixth People's Hospital, Shanghai, China.
Yan GuDepartment of General Surgery, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Rixing BaiDepartment of General Surgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Fanqiang MengDepartment of General Surgery, China-Japan Friendship Hospital, Beijing, China.
Zhongqi MaoDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Xiangwen ZhaoDepartment of General Surgery, Xiaolan People's Hospital, Guangdong, China.
Liangping WuDivision of Metabolic and Bariatric Surgery, Department of General Surgery, Jinshazhou Hospital of Guangzhou, University of Chinese Medicine, Guangdong, China.
Yanjun LiuCenter of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, The Third People's Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University & Research Center for Obesity and Metabolic Disease, School of Medicine, Southwest Jiaotong University, Sichuan, China.
Songhai ZhangDepartment of General Surgery, The First Affiliated Hospital of Henan University of Science and Technology, Henan, China.
Peng ZhangDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China zhangzht@ccmu.edu.cn zhangpg@yahoo.com.
Zhongtao ZhangDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China zhangzht@ccmu.edu.cn zhangpg@yahoo.com.ORCID 0000-0002-4718-6821

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrevious studies have demonstrated that one anastomosis gastric bypass (OAGB) is not inferior to Roux-en-Y gastric bypass (RYGB) in treating obesity. However, high level evidence comparing the efficacy and safety of both procedures in type 2 diabetes (T2D) treatment is still lacking, which is another main aim of bariatric surgery. The presented trial has been designed to aim at investigating the superiority of OAGB over the reference procedure RYGB in treating T2D as primary endpoint. And diabetes-related microvascular and macrovascular complications, cardiovascular comorbidities, weight loss, postoperative nutritional status, quality of life and overall complications will be followed up for 5 years as secondary endpoints. METHODS AND ANALYSIS: This prospective, multicentre, randomised superiority open-label trial will be conducted in patients of Asian descent. A total of 248 patients (BMI≥27.5 kg/m ETHICS AND DISSEMINATION: The study has been approved by the ethics committee of leading centre (Beijing Friendship Hospital, Capital Medical University, no. 2021-P2-037-03). The results generated from this work will be disseminated to academic audiences and the public via publications in international peer-reviewed journals and conferences. The data presented will be imported into a national data registry. Findings are expected to be available in 2025, which will facilitate clinical decision-making in the field. TRIAL REGISTRATION NUMBER: NCT05015283.

Indexed as

Diabetes Mellitus, Type 2Gastric BypassBlood GlucoseEquivalence Trials as TopicGlycated HemoglobinHumansHypoglycemic AgentsMulticenter Studies as TopicProspective StudiesQuality of LifeRandomized Controlled Trials as TopicBlood GlucoseGlycated HemoglobinHypoglycemic AgentsClinical trialsDIABETES & ENDOCRINOLOGYSURGERY

Identifiers

PMID36175102
PMCPMC9528602

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.