Evidence map›Paper›PMID 36178544›Full record

ArticleMycopathologia2022

Filamentous Fungal Keratitis in Greece: A 16-Year Nationwide Multicenter Survey.

Alexandra Mpakosi, Maria Siopi, Georgia Vrioni, Maria Orfanidou, Athina Argyropoulou, Myrto Christofidou, Maria Kostoula, Stamatina Golegou, Anastasia Antoniadou, Eleni Vagiakou and 8 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. A Rare Case ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Alexandra MpakosiInfectious Diseases Research Laboratory/4th Department of Internal Medicine, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, Rimini 1, 12462, Athens, Greece.
Maria SiopiClinical Microbiology Laboratory, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Georgia VrioniDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Maria OrfanidouClinical Microbiology Laboratory, General Hospital of Athens "Georgios Gennimatas", Athens, Greece.
Athina ArgyropoulouDepartment of Clinical Microbiology, Evangelismos General Hospital, Athens, Greece.
Myrto ChristofidouLaboratory of Microbiology, University Hospital of Patras, Patras, Greece.
Maria KostoulaAthens Eye Hospital, Glyfada, Greece.
Stamatina GolegouAgioi Anargyroi General Oncological Hospital of Kifissia, Kifissia, Greece.
Anastasia AntoniadouInfectious Diseases Research Laboratory/4th Department of Internal Medicine, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, Rimini 1, 12462, Athens, Greece.
Eleni VagiakouClinical Microbiology Laboratory, General Hospital of Athens "Georgios Gennimatas", Athens, Greece.
Eleni PetrouClinical Microbiology Laboratory, General Hospital of Athens "Georgios Gennimatas", Athens, Greece.
Evangelia PlatsoukaDepartment of Microbiology, General Hospital of Nea Ionia 'Konstantopouleio-Patission', Athens, Greece.
Eleni PapadogeorgakiHygeia General Hospital, Athens, Greece.
Joseph MeletiadisClinical Microbiology Laboratory, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Irini Chatziralli2nd Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, Greece.
Panagiotis Theodossiadis2nd Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, Greece.
Georgios PetrikkosInfectious Diseases Research Laboratory/4th Department of Internal Medicine, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, Rimini 1, 12462, Athens, Greece.
Maria Drogari-ApiranthitouInfectious Diseases Research Laboratory/4th Department of Internal Medicine, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, Rimini 1, 12462, Athens, Greece. mdrogari@hotmail.com.ORCID http://orcid.org/0000-0002-2082-4440

Funding

Gilead Sciences Hellas Μ.EPE ASKLEPIOS Programme, 2013
6 · The paper itself

Abstract

In a multicenter, prospective study of filamentous fungal keratitis in Greece, predisposing factors, etiology, treatment practices, and outcome, were determined. Corneal scrapings were collected from patients with clinical suspicion of fungal keratitis, and demographic and clinical data were recorded. Fungal identification was based on morphology, molecular methods, and matrix assisted laser desorption ionization time-of-flight mass-spectrometry. A total of 35 cases were identified in a 16-year study period. Female to male ratio was 1:1.7 and median age 48 years. Corneal injury by plant material, and soft contact lens use were the main risk factors (42.8% and 31.4%, respectively). Trauma was the leading risk factor for men (68.1%), contact lens use (61.5%) for women. Fusarium species were isolated more frequently (n = 21, 61.8%). F. solani was mostly associated with trauma, F. verticillioides and F. proliferatum with soft contact lens use. Other fungi were: Purpureocillium lilacinum (14.7%), Alternaria (11.8%), Aspergillus (8.8%), and Phoma foliaceiphila, Beauveria bassiana and Curvularia spicifera, one case each. Amphotericin B and voriconazole MIC

Indexed as

Corneal UlcerEye Infections, FungalFusariumKeratitisAlternariaAntifungal AgentsFemaleGreeceHumansMaleMiddle AgedProspective StudiesVoriconazoleAntifungal AgentsVoriconazoleEpidemiologyFilamentous fungiFungal keratitisFusariumGreecePurpureocillium lilacinum

Identifiers

PMID36178544

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.