Evidence mapPaperPMID 36187235Full record

ArticleBiomedical optics express2022

MF-AV-Net: an open-source deep learning network with multimodal fusion options for artery-vein segmentation in OCT angiography.

Mansour Abtahi, David Le, Jennifer I Lim, Xincheng Yao

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. OCTA-ReVABiomedical optics express · 2025
    Article
  3. Widefield OCT angiography.Progress in retinal and eye research · 2025
    Review
  4. Article
  5. Article
  6. Advances in OCT Angiography.Translational vision science & technology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mansour AbtahiDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID https://orcid.org/0000-0001-7463-9470
David LeDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Jennifer I LimDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA.
Xincheng YaoDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID https://orcid.org/0000-0002-0356-3242
University of Illinois Chicago · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · UNIVERSITY OF ILLINOIS AT CHICAGO · 1985 to 2025
$3.9M
Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathyR01EY030842 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jennifer Irene Lim, XINCHENG YAO · 2023 to 2023
$363k
Functional tomography of neurovascular coupling interactions in healthy and diseased retinasR01EY030101 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI XINCHENG YAO · 2022 to 2022
$304k
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY023522NEI NIH HHS R01 EY030101NEI NIH HHS R01 EY030842
6 · The paper itself

Abstract

This study is to demonstrate the effect of multimodal fusion on the performance of deep learning artery-vein (AV) segmentation in optical coherence tomography (OCT) and OCT angiography (OCTA); and to explore OCT/OCTA characteristics used in the deep learning AV segmentation. We quantitatively evaluated multimodal architectures with early and late OCT-OCTA fusions, compared to the unimodal architectures with OCT-only and OCTA-only inputs. The OCTA-only architecture, early OCT-OCTA fusion architecture, and late OCT-OCTA fusion architecture yielded competitive performances. For the 6 mm×6 mm and 3 mm×3 mm datasets, the late fusion architecture achieved an overall accuracy of 96.02% and 94.00%, slightly better than the OCTA-only architecture which achieved an overall accuracy of 95.76% and 93.79%. 6 mm×6 mm OCTA images show AV information at pre-capillary level structure, while 3 mm×3 mm OCTA images reveal AV information at capillary level detail. In order to interpret the deep learning performance, saliency maps were produced to identify OCT/OCTA image characteristics for AV segmentation. Comparative OCT and OCTA saliency maps support the capillary-free zone as one of the possible features for AV segmentation in OCTA. The deep learning network MF-AV-Net used in this study is available on GitHub for open access.

Identifiers

PMID36187235
PMCPMC9484445
OpenAlexW4291777774

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.