Evidence map›Paper›PMID 36189115›Full record

ArticleLancet regional health. Americas2022

An updated profile of the cancer burden, patterns and trends in Latin America and the Caribbean.

Marion Piñeros, Mathieu Laversanne, Enrique Barrios, Marianna de Camargo Cancela, Esther de Vries, Constanza Pardo, Freddie Bray

Abstract read
In one paragraph

Article in Lancet regional health. Americas, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. The GOG Foundation and EVA/LACOG partnership: a collaborative strategic alliance for clinical trial execution.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2026
    Article
  9. Occupational Cancer Mortality Trends in Brazil, 1990-2023.International journal of environmental research and public health · 2026
    Article
  10. Healthcare stakeholders' perspectives on coordinating cancer diagnosis in Chile, Colombia, and Ecuador.Revista panamericana de salud publica = Pan American journal of public health · 2026
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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marion PiñerosCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.
Mathieu LaversanneCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.
Enrique BarriosNational Cancer Registry, Honorary Commission for the Fight against Cancer, Montevideo, Uruguay.
Marianna de Camargo CancelaCancer Surveillance Division, National Cancer Institute INCA, Rio de Janeiro, Brasil.
Esther de VriesDepartment of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana, Bogotá, Colombia.
Constanza PardoCancer Surveillance Group, National Cancer Institute, INC Bogotá, Colombia.
Freddie BrayCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.

Funding

World Health Organization 001
6 · The paper itself

Abstract

Background: Cancer is a leading cause of disease and death in Latin America and the Caribbean (LAC). Contemporary data on the cancer burden aims to inform effective cancer policies; this article provides an update and benchmarking of national cancer incidence and mortality estimates for the year 2020, alongside recent mortality trends in the region. Methods: The number of new cancer cases and deaths were extracted from the GLOBOCAN 2020 database developed by the International Agency for Research on Cancer (IARC), and mortality data over time from IARC's cancer mortality database, New cancer cases, deaths and corresponding age-standardized rates per 100,000 person-years are presented. Random fluctuations in mortality trends by country, sex and cancer site were smoothed using LOWESS regression. Findings: An estimated total of 1.5 million new cancer cases and 700,000 deaths occur annually in LAC, with corresponding incidence and mortality rates of 186.5 and 86.6 per 100,000. The most common cancers in 2020 were prostate (15%), breast (14%), colorectal (9%), lung (7%) and stomach (5%). Lung cancer remained the leading cause of cancer death (12%), though rates varied substantially between countries. The mortality trends of infectious-related cancers tended to decline in most countries, while rates of cancer types linked to westernization were mainly increasing. Assuming rates remain unchanged, the cancer burden in LAC will increase by 67% reaching 2.4 million new cases annually by 2040. Interpretation: The cancer patterns reflect important underlying sociodemographic changes occurring over the last decades. With an increasing burden anticipated over the next decades in this region, there is a need to plan oncological service provision accordingly. Funding: No external funds received.

Indexed as

CancerEpidemiologyGlobal healthNeoplasmsPublic health surveillance

Identifiers

PMID36189115
PMCPMC9483035

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.