Evidence map›Paper›PMID 36190618›Full record

ArticleCell biochemistry and biophysics2022

The Role of Bystander Effect in Ultraviolet A Induced Photoaging.

Surajit Hansda, Gargi Ghosh, Rita Ghosh

Abstract read
PubMed Publisher
In one paragraph

Article in Cell biochemistry and biophysics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Journal of Taibah University Medical Sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Surajit HansdaDepartment of Biochemistry & Biophysics, University of Kalyani, Kalyani, 741235, West Bengal, India.
Gargi GhoshDepartment of Molecular Biology & Biotechnology, University of Kalyani, Kalyani, 741235, West Bengal, India.
Rita GhoshDepartment of Biochemistry & Biophysics, University of Kalyani, Kalyani, 741235, West Bengal, India. rghosh_bcbp@klyuniv.ac.in.ORCID http://orcid.org/0000-0002-7080-195X
University of Kalyani · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to sunlight, mainly UVA, leads to typical changes in the features of the skin known as photoaging. UVA irradiation induces the expression of proteases that are responsible for the degradation of the extracellular matrix proteins to results in photoaging; it also downregulates the expression of proteins that are needed for the skin structure. Since, it is known that cells in the neighborhood of irradiated cells, but not directly exposed to it, often manifest responses like their irradiated counterparts, it is important to evaluate if these bystander cells too, can contribute to photoaging. UVA induced cell cycle arrest has been associated with photoaging, from flow cytometry analysis we found that there was an induction of cell cycle arrest at the G

Indexed as

Skin AgingSkin DiseasesBystander EffectCyclooxygenase 2ElastinFibroblastsHumansMatrix Metalloproteinase 1Matrix Metalloproteinase 3Matrix Metalloproteinase 9SkinUltraviolet RaysCyclooxygenase 2ElastinMatrix Metalloproteinase 1Matrix Metalloproteinase 3Matrix Metalloproteinase 9Bystander responseCyclooxygenase-2 (COX-2)Matrix metalloproteinase-1 (MMP-1)PhotoagingUVA

Identifiers

PMID36190618
OpenAlexW4300689687

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.