Evidence map›Paper›PMID 36191724›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2023

Racial and Ethnic Disparities in Acute Care Utilization Among Patients With Glomerular Disease.

Jill R Krissberg, Michelle M O'Shaughnessy, Abigail R Smith, Margaret E Helmuth, Salem Almaani, Diego H Aviles, Kaye E Brathwaite, Yi Cai, Daniel Cattran, Rasheed Gbadegesin and 23 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Treatment Response Rates and Kidney Outcomes among Adults with Primary FSGS.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  2. KDOQI US Commentary on the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 20 institutions in 4 countries.

Jill R KrissbergDivision of Pediatric Nephrology, Anne & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois. Electronic address: jkrissberg@luriechildrens.org.
Michelle M O'ShaughnessyDepartment of Renal Medicine, Cork University Hospital, Ireland; and School of Medicine, University College Cork, Ireland.
Abigail R SmithArbor Research Collaborative for Health, Ann Arbor, Michigan.
Margaret E HelmuthArbor Research Collaborative for Health, Ann Arbor, Michigan.
Salem AlmaaniDivision of Nephrology, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Diego H AvilesLouisiana State University Health Sciences Center, New Orleans, Louisiana.
Kaye E BrathwaiteDivision of Pediatric/Nephrology, Children's Hospital at Montefiore/Einstein, Bronx, New York.
Yi CaiPediatric Nephrology, Dialysis and Transplantation, Helen DeVos Children's Hospital, Grand Rapids, Michigan.
Daniel CattranDivision of Nephrology, University Health Network, University Health Network and University of Toronto, Toronto, ON, Canada.
Rasheed GbadegesinDepartment of Pediatrics, Division of Nephrology, Duke University Medical Center, Durham, North Carolina.
Dorey A GlennDivision of Nephrology and Hypertension, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Larry A GreenbaumDivision of Pediatric Nephrology, Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia.
Sandra IragorriOregon Health and Science University, Portland, Oregon.
Koyal JainDivision of Nephrology and Hypertension, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Myda KhalidDepartment of Pediatrics, Division of Nephrology, Indiana University School of Medicine, Indianapolis, Indiana.
Jason KiddVirginia Commonwealth University, Richmond, Virginia.
Jeffrey KoppKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Richard LafayetteDepartment of Medicine, Division of Nephrology, Stanford University School of Medicine, Stanford, California.
Jerome C LaneDivision of Pediatric Nephrology, Anne & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
Francesca LuganiL'Unità Operativa Complessa Nefrology, Dialysis and Transplant, Laboratorio di Nefrologia Molecolare, Istituto Giannina Gaslini Istituto di Ricovero e Cura a Carattere Scientifico, Genoa, Italy.
Jordan G NestorDepartment of Medicine, Division of Nephrology, Columbia University, New York, New York.
Rulan S ParekhDivision of Nephrology, Department of Pediatrics and Medicine, Hospital for Sick Children, University Health Network and University of Toronto, Toronto, ON, Canada.
Kimberly ReidyDivision of Pediatric/Nephrology, Children's Hospital at Montefiore/Einstein, Bronx, New York.
David T SelewskiDepartment of Pediatrics, Division of Nephrology, Medical University of South Carolina, Charleston, South Carolina.
Christine B SethnaDivision of Pediatric Nephrology, Cohen Children's Medical Center, New Hyde Park, New York.
C John SperatiDivision of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Katherine TuttleProvidence Health Care, Department of Medicine, Division of Nephrology, University of Washington, Spokane and Seattle, Washington.
Katherine TwombleyDepartment of Pediatrics, Division of Nephrology, Medical University of South Carolina, Charleston, South Carolina.
Tetyana L VasylyevaDepartment of Pediatrics, Texas Tech University Health Sciences Center, Amarillo, Texas.
Donald J WeaverDivision of Pediatric Nephrology and Hypertension, Atrium Health Levine Children's, Charlotte, North Carolina.
Scott E WenderferDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas.
Keisha GibsonDepartment of Medicine and Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
CureGN Consortium
University of North Carolina at Chapel Hill · USJohns Hopkins University · USUniversity Health Network · CAUniversity College Cork · IENational Institutes of Health · USVirginia Commonwealth University · USAlbert Einstein College of Medicine · USArbor Research Collaborative for Health · USIndiana University School of MedicineLurie Children's Hospital · USMedical University of South Carolina · USBaylor College of Medicine · USCohen Children's Medical Center · USColumbia University · USDuke Medical Center · USEmory University · USHelen DeVos Children's Hospital · USIstituto Giannina Gaslini · ITLevine Children's Hospital · USLouisiana State University Health Sciences Center New Orleans · US

Funding

Institutional Career Development CoreKL2TR001874 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GENKINGER, JEANINE M., SHIMBO, DAICHI · 2016 to 2025
$13.6M
CureGNU24DK100845 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CRYSTAL A. GADEGBEKU, Laura H Mariani · 2019 to 2026
$12.1M
The Columbia PCC for CureGN: the Cure Glomerulonephropathy networkU01DK100876 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Andrew Stephen Bomback, ALI G GHARAVI · 2019 to 2026
$8.5M
CureGN-Penn PCCU01DK100846 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LAWRENCE B. HOLZMAN · 2019 to 2026
$8.3M
CUREGN 3.0 - Pediatric Nephrology Consortium - PCCU01DK100866 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Laurence A Greenbaum, Jon Klein · 2019 to 2026
$7.7M
CureGN-3: UNCPCCU01DK100867 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Vimal Kumar Derebail, Ronald J Falk · 2019 to 2026
$6.7M
GDPrimeUM1DK100845 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GIPSON, DEBBIE S, KRETZLER, MATTHIAS · 2013 to 2018
$6.4M
Primary Outcomes in Glomerulonephritis Study (PROGRESS)UM1DK100846 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI HOLZMAN, LAWRENCE B. · 2013 to 2018
$5.8M
DEVELOPMENTAL RENAL AND ELECTROLYTE PHYSIOLOGYT32DK007110 · NIDDK · YESHIVA UNIVERSITY · PI KASKEL, FREDERICK JEFFREY, MELAMED, MICHAL L · 1986 to 2021
$5.6M
Integrative Proteomics & Metabolomics for Pediatric Glomerula Disease BiomarkersUM1DK100866 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI GREENBAUM, LAURENCE A, SMOYER, WILLIAM E · 2013 to 2018
$5.5M
Advancing Clinical Research in Primary Glomerular Diseases (UM1)UM1DK100876 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GHARAVI, ALI G · 2013 to 2018
$4.8M
GDCN Clinical Center-Advancing Clinical Research in Primary Glomerular DiseasesUM1DK100867 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FALK, RONALD J · 2013 to 2018
$4.0M
NCATS NIH HHS KL2 TR001874NIAID NIH HHS K23 AI159073NIDDK NIH HHS T32 DK007110NIDDK NIH HHS U01 DK100846NIDDK NIH HHS U01 DK100866NIDDK NIH HHS U01 DK100867NIDDK NIH HHS U01 DK100876NIDDK NIH HHS U24 DK100845NIDDK NIH HHS UM1 DK100845NIDDK NIH HHS UM1 DK100846NIDDK NIH HHS UM1 DK100866NIDDK NIH HHS UM1 DK100867NIDDK NIH HHS UM1 DK100876
6 · The paper itself

Abstract

RATIONALE &

objectiveThe effects of race, ethnicity, socioeconomic status (SES), and disease severity on acute care utilization in patients with glomerular disease are unknown. STUDY

designProspective cohort study. SETTING &

participants1,456 adults and 768 children with biopsy-proven glomerular disease enrolled in the Cure Glomerulonephropathy (CureGN) cohort. EXPOSURE: Race and ethnicity as a participant-reported social factor. OUTCOME: Acute care utilization defined as hospitalizations or emergency department visits. ANALYTICAL APPROACH: Multivariable recurrent event proportional rate models were used to estimate associations between race and ethnicity and acute care utilization.

resultsBlack or Hispanic participants had lower SES and more severe glomerular disease than White or Asian participants. Acute care utilization rates were 45.6, 29.5, 25.8, and 19.2 per 100 person-years in Black, Hispanic, White, and Asian adults, respectively, and 55.8, 42.5, 40.8, and 13.0, respectively, for children. Compared with the White race (reference group), Black race was significantly associated with acute care utilization in adults (rate ratio [RR], 1.76 [95% CI, 1.37-2.27]), although this finding was attenuated after multivariable adjustment (RR, 1.31 [95% CI, 1.03-1.68]). Black race was not significantly associated with acute care utilization in children; Asian race was significantly associated with lower acute care utilization in children (RR, 0.32 [95% CI 0.14-0.70]); no significant associations between Hispanic ethnicity and acute care utilization were identified. LIMITATIONS: We used proxies for SES and lacked direct information on income, household unemployment, or disability.

conclusionsSignificant differences in acute care utilization rates were observed across racial and ethnic groups in persons with prevalent glomerular disease, although many of these difference were explained by differences in SES and disease severity. Measures to combat socioeconomic disadvantage in Black patients and to more effectively prevent and treat glomerular disease are needed to reduce disparities in acute care utilization, improve patient wellbeing, and reduce health care costs.

Indexed as

EthnicityHealthcare DisparitiesKidney DiseasesPatient Acceptance of Health CareAdultAsian PeopleBlack PeopleChildHispanic or LatinoHumansProspective StudiesSocial ClassWhite Peopleacute care utilization (ACU)adultschildrenED visitemergency department (ED)Glomerular diseasehealth care disparityhospitalizationmodifiable risk factorpediatricracial and ethnic disparitiessocial determinants of health (SDOH)socioeconomic status (SES)

Identifiers

PMID36191724
PMCPMC9974571
OpenAlexW4298122184

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.