Evidence map›Paper›PMID 36193063›Full record

ArticleOxidative medicine and cellular longevity2022

Tumor Necrosis Factor-Alpha Disrupts Cx43-Mediated Corneal Endothelial Gap Junction Intercellular Communication.

Jufeng Meng, Ke Xu, Yinyin Qin, Ya Liu, Lin Xu, Shigang Qiao, Jianzhong An, Jianjun Liu, Zhenhao Zhang

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jufeng Meng *School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.ORCID https://orcid.org/0000-0002-3035-7225
Ke Xu *Key Laboratory of Tropical Translational Medicine of Ministry of Education, NHC Key Laboratory of Control of Tropical Diseases, School of Tropical Medicine, Hainan Medical University, Haikou 571199, China.ORCID https://orcid.org/0000-0002-4423-1703
Yinyin QinInstitute of Clinical Medicine Research, Suzhou Science & Technology Town Hospital, Suzhou 215153, China.
Ya LiuDepartment of Ophthalmology, Suzhou Science & Technology Town Hospital, Suzhou 215153, China.
Lin XuDepartment of Ophthalmology, Suzhou Science & Technology Town Hospital, Suzhou 215153, China.
Shigang QiaoInstitute of Clinical Medicine Research, Suzhou Science & Technology Town Hospital, Suzhou 215153, China.ORCID https://orcid.org/0000-0003-0309-8405
Jianzhong AnInstitute of Clinical Medicine Research, Suzhou Science & Technology Town Hospital, Suzhou 215153, China.
Jianjun LiuDepartment of Ophthalmology, Suzhou Science & Technology Town Hospital, Suzhou 215153, China.
Zhenhao ZhangInstitute of Clinical Medicine Research, Suzhou Science & Technology Town Hospital, Suzhou 215153, China.ORCID https://orcid.org/0000-0001-5659-6315
Suzhou University of Science and Technology · CNHainan Medical University · CNShanghaiTech University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Connexin43 (Cx43)-mediated gap junctions are vital in maintaining corneal endothelium homeostasis. Tumor necrosis factor-alpha (TNF-

Indexed as

Connexin 43Tumor Necrosis Factor-alphaAnimalsCell CommunicationCells, CulturedGap JunctionsRabbitsConnexin 43Tumor Necrosis Factor-alpha

Identifiers

PMID36193063
PMCPMC9526630
OpenAlexW4296343840

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.