Evidence map›Paper›PMID 36194703›Full record

ArticleThe American journal of drug and alcohol abuse2023

Prenatal alcohol exposure causes persistent microglial activation and age- and sex- specific effects on cognition and metabolic outcomes in an Alzheimer's Disease mouse model.

Kathleen R Walter, Dane K Ricketts, Brandon H Presswood, Susan M Smith, Sandra M Mooney

Open access · greenAbstract read
In one paragraph

Article in The American journal of drug and alcohol abuse, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Adolescent Alcohol and the Spectrum of Cognitive Dysfunction in Aging.Advances in experimental medicine and biology · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Behavioral changes inFrontiers in neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kathleen R WalterUNC Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC, USA.ORCID 0000-0003-3461-1881
Dane K RickettsUNC Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC, USA.
Brandon H PresswoodUNC Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC, USA.
Susan M SmithUNC Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC, USA.
Sandra M MooneyUNC Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC, USA.ORCID 0000-0002-7387-2518
University of North Carolina at Chapel Hill · US

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Venkata Saroja Voruganti · 1999 to 2026
$31.6M
Craniofacial Morphogenesis in Prenatal Alcohol ExposureR01AA011085 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SMITH, SUSAN M. · 2001 to 2025
$6.3M
Craniofacial Morphogenesis in Prenatal Alcohol ExposureR37AA011085 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SMITH, SUSAN M. · 2007 to 2016
$3.3M
Nutrient combination to mitigate Fetal Alcohol Spectrum DisorderR01AA024980 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MOONEY, SANDRA M · 2017 to 2021
$2.3M
Experimental Factors in Fetal Alcohol Spectrum DisorderR01AA022413 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MOONEY, SANDRA M · 2014 to 2018
$1.7M
Prenatal alcohol exposure disrupts maternal-fetal iron metabolism in FASDR01AA022999 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KLING, PAMELA J, SMITH, SUSAN M. · 2014 to 2018
$1.6M
CRANIOFACIAL MORPHOGENESIS IN PRENATAL ALCOHOL EXPOSURER29AA011085 · NIAAA · UNIVERSITY OF WISCONSIN MADISON · PI SMITH, SUSAN M. · 1996 to 2000
$100k
NIAAA NIH HHS R01 AA011085NIAAA NIH HHS R01 AA022413NIAAA NIH HHS R01 AA022999NIAAA NIH HHS R01 AA024980NIAAA NIH HHS R29 AA011085NIAAA NIH HHS R37 AA011085NIDDK NIH HHS P30 DK056350
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseNeurodegenerative DiseasesPrenatal Exposure Delayed EffectsAnimalsCognitionDisease Models, AnimalEthanolFemaleGlucoseHumansMaleMiceMice, TransgenicMicrogliaPregnancyEthanolGlucoseagingAlzheimer’s diseasecognitive performancedevelopmental origins of health and diseasefetal alcohol syndromeglucose tolerancemetabolic syndromemicroglianeuroinflammationobesity

Identifiers

PMID36194703
PMCPMC11040461
OpenAlexW4301182689

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.