Evidence map›Paper›PMID 36195237›Full record

ReviewThe ocular surface2022

Recent advances in optical coherence tomography for anterior segment imaging in small animals and their clinical implications.

Lisa Beckmann, Zhen Cai, Mathew Margolis, Raymond Fang, Ali Djalilian, Hao F Zhang

Abstract readReview
In one paragraph

Review in The ocular surface, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lisa BeckmannDepartment of Biomedical Engineering, Northwestern University, Evanston IL, USA.
Zhen CaiDepartment of Biomedical Engineering, Northwestern University, Evanston IL, USA; Currently with Department of Ophthalmology, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan, Hubei, China.
Mathew MargolisDepartment of Ophthalmology and Visual Science, University of Illinois at Chicago, Chicago IL, USA.
Raymond FangDepartment of Biomedical Engineering, Northwestern University, Evanston IL, USA.
Ali DjalilianDepartment of Ophthalmology and Visual Science, University of Illinois at Chicago, Chicago IL, USA.
Hao F ZhangDepartment of Biomedical Engineering, Northwestern University, Evanston IL, USA. Electronic address: hfzhang@northwestern.edu.

Funding

Novel Glaucoma Diagnostics for Structure and Function - Renewal - 1R01EY013178 · NEI · WILLS EYE HEALTH SYSTEM · PI Joel S Schuman · 2000 to 2026
$17.5M
Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SHUKLA, DEEPAK · 1985 to 2025
$14.8M
ER Stress and Diabetic RetinopathyR01EY019949 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ZHANG, SARAH X · 2010 to 2023
$5.5M
Clinical glaucoma management enabled by visible-light OCTU01EY033001 · NEI · NORTHWESTERN UNIVERSITY · PI SCHUMAN, JOEL S, ZHANG, HAO F · 2021 to 2025
$3.2M
Visible-light optical coherence tomography for clinical glaucoma managementR44EY026466 · NEI · OPTICENT, INC. · PI KURANOV, ROMAN · 2018 to 2023
$2.7M
Novel ocular imaging and molecular analysis of anterior eye segment for glaucomaR01EY034740 · NEI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Tsutomu Kume, Hao F Zhang · 2023 to 2026
$2.7M
Investigating oxygen metabolism in diabetic retinopathyR01EY026078 · NEI · NORTHWESTERN UNIVERSITY · PI SHEIBANI, NADER, ZHANG, HAO F · 2016 to 2020
$2.3M
Novel Therapies for Ocular Chemical InjuriesR01EY024349 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DJALILIAN, ALI R · 2015 to 2020
$2.1M
Investigating nanoscale neuronal damages in early glaucoma towards clinical optical detectionR01EY029121 · NEI · NORTHWESTERN UNIVERSITY · PI LIU, XIAORONG, ZHANG, HAO F · 2018 to 2021
$2.0M
Physical Genomics and Engineering Training ProgramT32GM142604 · NIGMS · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM · 2021 to 2025
$1.9M
Mechanisms underlying the formation of the cornea and ocular surface epitheliumR01EY028304 · NEI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KUME, TSUTOMU · 2018 to 2021
$1.6M
Visual Sciences T32T32EY025202 · NEI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Gregory William Schwartz · 2015 to 2026
$1.4M
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY013178NEI NIH HHS R01 EY019949NEI NIH HHS R01 EY024349NEI NIH HHS R01 EY026078NEI NIH HHS R01 EY028304NEI NIH HHS R01 EY029121NEI NIH HHS R01 EY034740NEI NIH HHS R44 EY026466NEI NIH HHS T32 EY025202NEI NIH HHS U01 EY033001NIGMS NIH HHS T32 GM142604
6 · The paper itself

Abstract

Anterior segment optical coherence tomography (AS-OCT) is a rapidly evolving area of OCT imaging, providing high-resolution and non-invasive volumetric imaging of the anterior segment. This review focuses on recent advances in AS-OCT imaging in small animals, which we categorize into ultrahigh-resolution, spectroscopic, magnetomotive, polarization-sensitive, and angiographic AS-OCTs. We summarize their technical foundations, review their applications to small animal imaging, and briefly discuss their current and future clinical applications.

Indexed as

Anterior Eye SegmentTomography, Optical CoherenceAnimalsAnimal modelAnterior segmentOptical coherence tomography

Identifiers

PMID36195237
PMCPMC10040227

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.