Evidence map›Paper›PMID 36197944›Full record

ArticlePloS one2022

Developing EMR-based algorithms to Identify hospital adverse events for health system performance evaluation and improvement: Study protocol.

Guosong Wu, Cathy Eastwood, Yong Zeng, Hude Quan, Quan Long, Zilong Zhang, William A Ghali, Jeffrey Bakal, Bastien Boussat, Ward Flemons and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Guosong WuCentre for Health Informatics, Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-0440-0784
Cathy EastwoodCentre for Health Informatics, Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Yong ZengConcordia Institute for Information Systems Engineering, Gina Cody School of Engineering and Computer Science, Concordia University, Montreal, Quebec, Canada.
Hude QuanCentre for Health Informatics, Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Quan LongDepartment of Biochemistry and Molecular Biology, Department of Medical Genetics, Department of Mathematics and Statistics, University of Calgary, Calgary, Alberta, Canada.
Zilong ZhangCentre for Health Informatics, Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
William A GhaliOffice of Vice President of Research & O'Brien Institute of Public Health, University of Calgary, Calgary, Alberta, Canada.
Jeffrey BakalCentre for Health Informatics, Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-3658-2554
Bastien BoussatClinical Epidemiology and Quality of Care Unit, University Grenoble Alpes, Faculty of Medicine, Grenoble University Hospital, France.
Ward FlemonsDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Alan ForsterDepartment of Clinical Epidemiology, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Danielle A SouthernCentre for Health Informatics, Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Søren KnudsenDigital Design Department, IT University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-8306-1102
Brittany PopowichCentre for Health Informatics, Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Yuan XuCentre for Health Informatics, Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-2100-9437
University of Calgary · CAAlberta Health Services · CACentre Hospitalier Universitaire de Grenoble · FRConcordia University · CAIT University of Copenhagen · DKOttawa Hospital · CA

Funding

CIHR DC0190GP
6 · The paper itself

Abstract

backgroundMeasurement of care quality and safety mainly relies on abstracted administrative data. However, it is well studied that administrative data-based adverse event (AE) detection methods are suboptimal due to lack of clinical information. Electronic medical records (EMR) have been widely implemented and contain detailed and comprehensive information regarding all aspects of patient care, offering a valuable complement to administrative data. Harnessing the rich clinical data in EMRs offers a unique opportunity to improve detection, identify possible risk factors of AE and enhance surveillance. However, the methodological tools for detection of AEs within EMR need to be developed and validated. The objectives of this study are to develop EMR-based AE algorithms from hospital EMR data and assess AE algorithm's validity in Canadian EMR data.

methodsPatient EMR structured and text data from acute care hospitals in Calgary, Alberta, Canada will be linked with discharge abstract data (DAD) between 2010 and 2020 (n~1.5 million). AE algorithms development. First, a comprehensive list of AEs will be generated through a systematic literature review and expert recommendations. Second, these AEs will be mapped to EMR free texts using Natural Language Processing (NLP) technologies. Finally, an expert panel will assess the clinical relevance of the developed NLP algorithms. AE algorithms validation: We will test the newly developed AE algorithms on 10,000 randomly selected EMRs between 2010 to 2020 from Calgary, Alberta. Trained reviewers will review the selected 10,000 EMR charts to identify AEs that had occurred during hospitalization. Performance indicators (e.g., sensitivity, specificity, positive predictive value, negative predictive value, F1 score, etc.) of the developed AE algorithms will be assessed using chart review data as the reference standard. DISCUSSION: The results of this project can be widely implemented in EMR based healthcare system to accurately and timely detect in-hospital AEs.

Indexed as

Electronic Health RecordsNatural Language ProcessingAlbertaAlgorithmsHospitalsHumansSystematic Reviews as Topic

Identifiers

PMID36197944
PMCPMC9534418
OpenAlexW4302012063

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.