Evidence map›Paper›PMID 36204282›Full record

ReviewAnimal nutrition (Zhongguo xu mu shou yi xue hui)2022

Paternal transgenerational nutritional epigenetic effect: A new insight into nutritional manipulation to reduce the use of antibiotics in animal feeding.

Xinyi Li, Mengya Wang, Shimin Liu, Xiaodong Chen, Yu Qiao, Xiaojun Yang, Junhu Yao, Shengru Wu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Transgenerational Impact of Environmental Change.Advances in experimental medicine and biology · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Xinyi LiCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Mengya WangCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Shimin LiuInstitute of Agriculture, University of Western Australia, Crawley, WA 6009, Australia.
Xiaodong ChenCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Yu QiaoCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Xiaojun YangCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Junhu YaoCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Shengru WuCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Northwest A&F University · CNKarolinska Institutet · SEThe University of Western Australia · AUYangzhou Vocational University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of antibiotics in animal feeding has been banned in many countries because of increasing concerns about the development of bacterial resistance to antibiotics and potential issues on food safety. Searching for antibiotic substitutes is essential. Applying transgenerational epigenetic technology to animal production could be an alternative. Some environmental changes can be transferred to memory-like responses in the offspring through epigenetic mechanisms without changing the DNA sequence. In this paper, we reviewed those nutrients and non-nutritional additives that have transgenerational epigenetic effects, including some amino acids, vitamins, and polysaccharides. The paternal transgenerational nutritional epigenetic regulation was particularly focused on mechanism of the substantial contribution of male stud animals to the animal industries. We illustrated the effects of paternal transgenerational epigenetics on the metabolism and immunity in farming animals and proposed strategies to modulate male breeding livestock or poultry.

Indexed as

Antibiotic replacementGrowthImmuneNutritionTransgenerational epigenetic

Identifiers

PMID36204282
PMCPMC9527621
OpenAlexW4286436597

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.