Evidence mapPaperPMID 36204587Full record

ReviewFrontiers in cardiovascular medicine2022

NF-κB and its crosstalk with endoplasmic reticulum stress in atherosclerosis.

Wenjing Li, Kehan Jin, Jichang Luo, Wenlong Xu, Yujie Wu, Jia Zhou, Yilin Wang, Ran Xu, Liqun Jiao, Tao Wang and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Wenjing LiLaboratory of Computational Biology and Machine Intelligence, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
Kehan JinPeking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Jichang LuoDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Wenlong XuDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yujie WuLaboratory of Computational Biology and Machine Intelligence, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
Jia ZhouPeking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Yilin WangInstitute of Cerebrovascular Disease Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.
Ran XuDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Liqun JiaoDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Tao WangDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Ge YangLaboratory of Computational Biology and Machine Intelligence, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
Capital Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNInstitute of Automation · CNBeijing Academy of Artificial Intelligence · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis (AS) is a common cardiovascular disease with complex pathogenesis, in which multiple pathways and their interweaving regulatory mechanism remain unclear. The primary transcription factor NF-κB plays a critical role in AS

Indexed as

atherosclerosisendoplasmic reticulum stressNF-κBNLRP3 inflammasomereactive oxygen speciesunfolded protein response

Identifiers

PMID36204587
PMCPMC9530249
OpenAlexW4296389389

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.