Evidence map›Paper›PMID 36212039›Full record

ArticleFrontiers in aging neuroscience2022

Association of

Changying Chen, Xuemei Chen, Siyuan Yang, Qingqing Li, Zhanyun Ren, Lu Wang, Yuzhang Jiang, Xincheng Gu, Fangyuan Liu, Jialing Mu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. SNP rs3803264 polymorphisms inFrontiers in aging neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Changying ChenDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Xuemei ChenDepartment of Neurology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Siyuan YangDepartment of Neurology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Qingqing LiDepartment of Neurology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Zhanyun RenDepartment of Neurology, The Affiliated Yixing Hospital of Jiangsu University, Yixing, China.
Lu WangDepartment of Neurology, Jurong Hospital Affiliated to Jiangsu University, Jurong People's Hospital, Jurong, China.
Yuzhang JiangDepartment of Medical Laboratory, Huai'an First People's Hospital, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an, China.
Xincheng GuDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Fangyuan LiuDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Jialing MuDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Lihua LiuDepartment of Neurology, Jurong Hospital Affiliated to Jiangsu University, Jurong People's Hospital, Jurong, China.
Yi WangDepartment of Neurology, Jurong Hospital Affiliated to Jiangsu University, Jurong People's Hospital, Jurong, China.
Junrong LiDepartment of Neurology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Yanhua YuDepartment of Neurology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Jun ZhangSuzhou Center for Disease Control and Prevention, Suzhou, China.
Chong ShenDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNJiangsu University · CNXuzhou Medical College · CNHuaian First People’s Hospital · CNNanjing Jiangning Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Thrombospondin-1 (THBS1) derived from platelets and acted as a critical mediator of hemostasis promoting platelet activation in thrombus formation. The biological connection of genetic variants and mRNA expression of Objective: To evaluate the association of single nucleotide polymorphisms (SNPs) and mRNA expression of Methods: A case-control study consisted of 4,584 IS patients recruited from five hospitals in Jiangsu, China, and 4,663 age-gender-matched controls free of IS. A cohort study enrolled 4,098 participants free of stroke and lasted from 2009 to 2022. Early collected 3158 IS patients aged between 35 and 80 years were followed up an average of 5.86-year to follow up their long-term death outcomes. Two tagSNPs of the Results: There is no significant difference in genotype and haplotype frequencies of rs2236741 and rs3743125 between IS cases and controls (all Conclusion: Therefore, our study suggested that there is no significant association of

Indexed as

case control studycohort studyischemic strokemRNA expressionthrombospondin-1

Identifiers

PMID36212039
PMCPMC9545898
OpenAlexW4296995264

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.