ReviewMayo Clinic proceedings2022
Long-term Medical Outcomes of Living Kidney Donors.
Review in Mayo Clinic proceedings, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Aortic stiffness after living kidney donation: a systematic review and meta-analysis.BMJ open · 2024Pooled it
- Long Term Outcomes in Living Kidney Donors Over 30 Years.Kidney international reports · 2026Article
- Early postoperative renal function is associated with long-term outcomes in living kidney donors.BMC nephrology · 2026Article
- Psychosocial Health and Quality of Life Among Living Kidney Donors: A Study From a Tertiary Care Center in South India.Kidney medicine · 2026Article
- Is it ethically permissible for GPs to promote non-directed altruistic kidney donation to healthy adults?Journal of medical ethics · 2026Article
- Clinical outcomes of living kidney transplantation from donors aged 70 years and older: a Japanese multicenter study.Scientific reports · 2025Observational
- Long-Term Outcomes of Living Kidney Donors in a Developing Country: A Single-Center Study.Journal of clinical medicine · 2025Article
- Similarities and Differences Between Allogeneic Hematopoietic Cell and Organ Transplantation and What We Can Learn From Each Other to Guide Global Health Strategy.Clinical transplantation · 2025Review
- Alternate Choice Organ Counselling in Altruistic Non-Directed Solid Organ Donation: An Ethical Analysis.Journal of evaluation in clinical practice · 2025Article
- Living Kidney Donation: A Narrative Review of Mid- and Long-term Psychosocial Outcomes.Transplantation · 2025Review
- Evaluating Risk in Kidney Living Donors.Transplant international : official journal of the European Society for Organ Transplantation · 2025Review
- A comprehensive review on indigenous therapeutic approaches in kidney care using Ayush medicine.Frontiers in pharmacology · 2025Review
- Risk of new onset hyperuricemia and chronic kidney disease after living kidney donation through propensity score matching analysis.Scientific reports · 2024Article
- Non-Maleficence toward Young Kidney Donors: A Call for Stronger Ethical Standards and Associated Factors in Multidisciplinary Nephrology Teams.Nursing reports (Pavia, Italy) · 2024Article
- The Ultrasound Renal Stress Test for the Assessment of Functional Renal Reserve in Kidney Transplantation: A Pilot Study in Living Donors.Journal of clinical medicine · 2024Article
- Risk factors for lower renal compensation after nephrectomy: an analysis of living kidney donors in an Amazonian cohort.Jornal brasileiro de nefrologia · 2024Observational
- The APOL1 gene and kidney transplantation: a review article.Jornal brasileiro de nefrologiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Historically, to minimize risks, living kidney donors have been highly selected and healthy. Operative risks are well-defined, yet concern remains about long-term risks. In the general population, even a mild reduction in glomerular filtration rate (GFR) is associated with cardiovascular disease, chronic kidney disease, and end-stage kidney disease (ESKD). However, reduction in GFR in the general population is due to kidney or systemic disease. Retrospective studies comparing donors with matched general population controls have found no increased donor risk. Prospective studies comparing donors with controls (maximum follow-up, 9 years) have reported that donor GFR is stable or increases slightly, whereas GFR decreases in controls. However, these same studies identified metabolic and vascular donor abnormalities. There are a few retrospective studies comparing donors with controls. Each has limitations in selection of the control group, statistical analyses, and/or length of follow-up. One such study reported increased donor mortality; 2 reported a small increase in absolute risk of ESKD. Risk factors for donor ESKD are similar to those in the general population. Postdonation pregnancies are also associated with increased risk of hypertension and preeclampsia. There is a critical need for long-term follow-up studies comparing donors with controls from the same era, geographic area, and socioeconomic status who are healthy, with normal renal function on the date matching the date of donation, and are matched on demographic characteristics with the donors. These data are needed to optimize donor candidate counseling and informed consent.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.