Evidence map›Paper›PMID 36218199›Full record

ReviewJournal of clinical ultrasound : JCU2022

Cardiorenal syndrome: Pathophysiology as a key to the therapeutic approach in an under-diagnosed disease.

Maria Prastaro, Ermanno Nardi, Stefania Paolillo, Ciro Santoro, Antonio L M Parlati, Paola Gargiulo, Christian Basile, Davide Buonocore, Giovanni Esposito, Pasquale Perrone Filardi

Abstract readReview
In one paragraph

Review in Journal of clinical ultrasound : JCU, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Observational
  5. Impact of Heart Failure and Chronic Kidney Disease on All-Cause Mortality in Patients Undergoing Coronary Angiography: Results From the Finnish Kardio Multicentre Registry.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
  6. Review
  7. Article
  8. Heart Failure-Focus on Kidney Replacement Therapy: Why, When, and How?International journal of molecular sciences · 2025
    Review
  9. Article
  10. Review
  11. NADCell communication and signaling : CCS · 2024
    Review
  12. Article
  13. Predictors of mortality in heart failure patients with reduced or mildly reduced Ejection Fraction: The CASABLANCA HF Study.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Article
  14. Article
  15. Article
  16. New Insight in Cardiorenal Syndrome: From Biomarkers to Therapy.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria PrastaroDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Ermanno NardiDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Stefania PaolilloDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Ciro SantoroDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.ORCID https://orcid.org/0000-0002-6329-1680
Antonio L M ParlatiDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Paola GargiuloDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Christian BasileDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Davide BuonocoreDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Giovanni EspositoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Pasquale Perrone FilardiDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiorenal syndrome is a clinical condition that impacts both the heart and the kidneys. One organ's chronic or acute impairment can lead to the other's chronic or acute dysregulation. The cardiorenal syndrome has been grouped into five subcategories that describe the etiology, pathophysiology, duration, and pattern of cardiac and renal dysfunction. This classification reflects the large spectrum of interrelated dysfunctions and underlines the bidirectional nature of heart-kidney interactions. However, more evidence is needed to apply these early findings in medical practice. Understanding the relationship between these two organs during each organ's impairment has significant clinical implications that are relevant for therapy in both chronic and acute conditions. The epidemiology, definition, classification, pathophysiology, therapy, and outcome of each form of cardiorenal syndrome are all examined in this review.

Indexed as

Cardio-Renal SyndromeHeart FailureAcute DiseaseHeartHumansKidneyacute kidney diseasecardiorenal syndromecardiovascular diseasechronic kidney diseaseheart failure

Identifiers

PMID36218199
PMCPMC9828083

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.