Evidence map›Paper›PMID 36219335›Full record

ArticleCEN case reports2023

Comparison of renal histopathology in three patients with gross hematuria after SARS-CoV-2 vaccination.

Kento Ota, Yuriko Yonekura, Madoka Saigan, Kimihiko Goto, Shinichi Nishi

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in CEN case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kento OtaDivision of Nephrology, Department of Medicine, Akashi Medical Center, 743-33, Yagi, Ohkubo-cho, Akashi, Hyogo, 674-0063, Japan.
Yuriko YonekuraDivision of Nephrology, Department of Medicine, Akashi Medical Center, 743-33, Yagi, Ohkubo-cho, Akashi, Hyogo, 674-0063, Japan. yo9ne4@gmail.com.ORCID 0000-0003-2677-7830
Madoka SaiganDivision of Nephrology, Department of Medicine, Akashi Medical Center, 743-33, Yagi, Ohkubo-cho, Akashi, Hyogo, 674-0063, Japan.
Kimihiko GotoDivision of Nephrology, Department of Medicine, Akashi Medical Center, 743-33, Yagi, Ohkubo-cho, Akashi, Hyogo, 674-0063, Japan.
Shinichi NishiDivision of Nephrology and Kidney Center, Kobe University Graduate School of Medicine, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan.
Akashi Medical Center · JPKobe University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present three cases of IgA nephropathy with gross hematuria following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger RNA (mRNA) vaccination. Case 1 was a 60-year-old woman who has previously experienced transient proteinuria. Case 2 was a 22-year-old woman with no history of urinary abnormality. Finally, case 3 was a 66-year-old woman who has had microscopic hematuria since she was in her 50s. They were all diagnosed as IgA nephropathy with little histological active lesion. Their renal function and proteinuria improved without the use of corticosteroids. There were differences in the findings of vascular endothelial damage based on the time between the appearance of gross hematuria and renal biopsy. Glomerular endocapillary damage could be a part of the mechanism triggered by mRNA vaccination. When a patient presents with gross hematuria following vaccination, a comprehensive approach including renal biopsy should be considered.

Indexed as

COVID-19Glomerulonephritis, IGAAdultAgedCOVID-19 VaccinesFemaleHematuriaHumansKidneyMiddle AgedProteinuriaSARS-CoV-2VaccinationYoung AdultCOVID-19 VaccinesGross hematuriaIgA nephropathySARS-CoV-2 vaccine

Identifiers

PMID36219335
PMCPMC9552725
OpenAlexW4304196111

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.