Evidence map›Paper›PMID 36220302›Full record

ReviewCold Spring Harbor perspectives in biology2023

The Wound Microbiome.

Ellen K White, Elizabeth A Grice

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. TiONanomaterials (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Review
  13. Review
  14. Science advances · 2024
    Article
  15. Article
  16. Community assembly of the human piercing microbiome.Proceedings. Biological sciences · 2023
    Article
  17. Article
  18. Review
  19. Review
  20. The heterogeneous wound microbiome varies with wound care pain, dressing type, and inflammatory gene expression.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ellen K WhiteDepartment of Dermatology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA.
Elizabeth A GriceDepartment of Dermatology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA egrice@pennmedicine.upenn.edu.

Funding

Skin microbiome contributions to the pathogenesis of cutaneous leishmaniasisR01AI143790 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Elizabeth Anne Grice, PHILLIP SCOTT · 2019 to 2026
$6.0M
Decoding the microbial burden in diabetic foot ulcersR01NR015639 · NINR · UNIVERSITY OF PENNSYLVANIA · PI GRICE, ELIZABETH ANNE · 2015 to 2023
$4.1M
Microbial regulation of the keratinocyte AHRR01AR079856 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI Elizabeth Anne Grice, THOMAS R SUTTER · 2022 to 2026
$2.7M
Skin microbial-based mechanisms of accelerated wound healingF31AR079852 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI WHITE, ELLEN · 2022 to 2023
$49k
NIAID NIH HHS R01 AI143790NIAMS NIH HHS F31 AR079852NIAMS NIH HHS R01 AR079856NINR NIH HHS R01 NR015639
6 · The paper itself

Abstract

Breach of the skin barrier and subsequent wound healing occur in the context of microbial communities of bacteria, fungi, and viruses. These polymicrobial communities are dynamic and important components of the wound environment and are associated with differential healing outcomes. Here, we highlight both culture-dependent and -independent methods that have furthered our understanding of the wound microbiome. We discuss common themes that have developed from such studies about the microbial inhabitants of diverse wound types. We additionally explore the wide range of microbial mechanisms that influence healing, from invading pathogens to beneficial commensals. These insights can be leveraged to better predict healing outcomes and derive novel microbial-based therapies for chronic wounds.

Indexed as

MicrobiotaBacteriaFungiWound Healing

Identifiers

PMID36220302
PMCPMC10394099

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.