Evidence map›Paper›PMID 36225603›Full record

ArticleFrontiers in bioengineering and biotechnology2022

3D

Erwin Pavel Lamparelli, Maria Camilla Ciardulli, Valentina Giudice, Pasqualina Scala, Rosa Vitolo, Tina Patricia Dale, Carmine Selleri, Nicholas Robert Forsyth, Nicola Maffulli, Giovanna Della Porta

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Umbilical Cord Tensile Strength Under Varying Strain Rates.Bioengineering (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Erwin Pavel LamparelliDepartment of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.
Maria Camilla CiardulliDepartment of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.
Valentina GiudiceDepartment of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.
Pasqualina ScalaDepartment of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.
Rosa VitoloDepartment of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.
Tina Patricia DaleGuy Hilton Research Centre, School of Pharmacy and Bioengineering, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom.
Carmine SelleriDepartment of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.
Nicholas Robert ForsythGuy Hilton Research Centre, School of Pharmacy and Bioengineering, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom.
Nicola MaffulliDepartment of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.
Giovanna Della PortaDepartment of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, chondrogenic potentials of 3D high-density cultures of Bone Marrow (BM) and Wharton's Jelly (WJ)-derived mesenchymal stromal cells (MSCs) was investigated by chondrogenesis- and cytokine-related gene expression over a 16-day culture period supplemented with human transforming growth factor (hTGF)-β1 at 10 ng/ml. In BM-MSC 3D models, a marked upregulation of chondrogenesis-related genes, such as

Indexed as

3D cell culturechondrogenesiscytokineshTGF-β1human bone marrow mesenchymal stem cellshuman Wharton’s jelly mesenchymal stem cells

Identifiers

PMID36225603
PMCPMC9549977

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.