Evidence map›Paper›PMID 36225648›Full record

ReviewAmerican journal of cancer research2022

Nanobiotherapeutic strategies to target immune microenvironment of triple-negative breast cancer.

Qing Chang, Liang Chang, Mo Li, Liwen Fan, Shunchao Bao, Xinyu Wang, Linlin Liu

Abstract readReview
In one paragraph

Review in American journal of cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qing ChangDepartment of Radiotherapy, China-Japan Union Hospital of Jilin University Changchun, Jilin, China.
Liang ChangXi'an Technological University Xi'an, Shanxi, China.
Mo LiThe Second Hospital of Jilin University Changchun, Jilin, China.
Liwen FanDepartment of Radiotherapy, China-Japan Union Hospital of Jilin University Changchun, Jilin, China.
Shunchao BaoDepartment of Radiotherapy, China-Japan Union Hospital of Jilin University Changchun, Jilin, China.
Xinyu WangThe Second Hospital of Jilin University Changchun, Jilin, China.
Linlin LiuDepartment of Radiotherapy, China-Japan Union Hospital of Jilin University Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is the subtype with the least favourable outcomes in breast cancer. Besides chemotherapy, there is a chronic lack of other effective treatments. Advances in omic technologies have liberated us from the ambiguity of TNBC heterogeneity in terms of cancer cell and immune microenvironment in recent years. This new understanding of TNBC pathology has already led to the exploitation of novel nanoparticulate systems, including tumor vaccines, oncolytic viruses, and antibody derivatives. The revolutionary ideas in the therapeutic landscape provide new opportunities for TNBC patients. Translating these experimental medicines into clinical benefit is both appreciated and challenging. In this review, we describe the prospective nanobiotherapy of TNBC that has been developed to overcome clinical obstacles, and provide our vision for this booming field at the overlap of cancer biotherapy and nanomaterial design.

Indexed as

biotherapy strategiesnanotechnologyTriple-negative breast cancertumor immune microenvironment

Identifiers

PMID36225648
PMCPMC9548023

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.