Evidence map›Paper›PMID 36227406›Full record

ReviewCurrent cardiology reports2022

Therapeutic Effects of Lipid Lowering Medications on Myocardial Blood Flow, Inflammation, and Sympathetic Nerve Activity Using Nuclear Techniques.

Takahiro Higuchi, Sebastian E Serfling, Steven P Rowe, Rudolf A Werner

Open access · hybridFull text readReview
In one paragraph

Review in Current cardiology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Takahiro HiguchiDepartment of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacherstr. 6, 97080, Würzburg, Germany.
Sebastian E SerflingDepartment of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacherstr. 6, 97080, Würzburg, Germany.
Steven P RoweThe Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Rudolf A WernerDepartment of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacherstr. 6, 97080, Würzburg, Germany. werner_r1@ukw.de.ORCID 0000-0003-3372-6046
Johns Hopkins University · USOkayama University · JPUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewStatins are routinely applied in patients with coronary artery disease, as they allow significantly to reduce blood cholesterol levels. Although those drugs are endorsed by current guidelines and prescribed routinely, a substantial portion of patients are still statin-intolerant and image-piloted strategies may then be helpful to identify patients that need further intensified treatment, e.g., to initiate treatment with proprotein convertase subtilisin / kexin type 9 inhibitors (PCSK9i). In addition, it has also been advocated that statins exhibit nonlipid, cardio-protective effects including improved cardiac nerve integrity, blood flow, and anti-inflammatory effects in congestive heart failure (HF) patients. RECENT

findingsIn subjects after myocardial infarction treated with statins,

Indexed as

Heart FailureHydroxymethylglutaryl-CoA Reductase Inhibitors3-IodobenzylguanidineHumansInflammationIodine RadioisotopesLipidsSympathetic Nervous System3-IodobenzylguanidineHydroxymethylglutaryl-CoA Reductase InhibitorsIodine-123Iodine RadioisotopesLipidsBlood flowCardiac nerveInflammationMIBGStatinSympathetic nervous system

Identifiers

PMID36227406
PMCPMC9747860
OpenAlexW4304956767

What Socratic holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.