Evidence map›Paper›PMID 36228315›Full record

GuidelineEuropean thyroid journal2022

2022 European Thyroid Association Guidelines for the management of pediatric thyroid nodules and differentiated thyroid carcinoma.

Chantal A Lebbink, Thera P Links, Agnieszka Czarniecka, Renuka P Dias, Rossella Elisei, Louise Izatt, Heiko Krude, Kerstin Lorenz, Markus Luster, Kate Newbold and 6 more

Abstract readGuideline
In one paragraph

Guideline in European thyroid journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Evolving trends in pediatric thyroid nodules and cancer management.Annals of pediatric endocrinology & metabolism · 2026
    Article
  14. Article
  15. Article
  16. DNA Methylation-Based Risk Stratification and Classification of Pediatric Thyroid Carcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Article
  17. Review
  18. Article
  19. Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Chantal A LebbinkWilhelmina Children's Hospital and Princess Máxima Center, Utrecht, The Netherlands.
Thera P LinksDepartment of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-5327-1718
Agnieszka CzarnieckaThe Oncologic and Reconstructive Surgery Clinic, M. Sklodowska-Curie National Research Institute of Oncology Gliwice Branch, Gliwice, Poland.
Renuka P DiasDepartment of Paediatric Endocrinology and Diabetes, Birmingham Children's Hospital NHS Foundation Trust, Birmingham, United Kingdom.
Rossella EliseiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Louise IzattDepartment of Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Heiko KrudeInstitute of Experimental Pediatric Endocrinology, Charité - Universitätsmedizin, Berlin, Germany.
Kerstin LorenzDepartment of Visceral, Vascular and Endocrine Surgery, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Markus LusterDepartment of Nuclear Medicine, University Hospital Marburg, Marburg, Germany.
Kate NewboldThyroid Therapy Unit, The Royal Marsden NHS Foundation Trust, London, United Kingdom.
Arnoldo PiccardoDepartment of Nuclear Medicine, EO Ospedali Galliera, Genoa, Italy.
Manuel Sobrinho-SimõesUniversity Hospital of São João, Medical Faculty and Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal.
Toru TakanoThyroid Center, Rinku General Medical Center, Osaka, Japan.
A S Paul van TrotsenburgDepartment of Pediatric Endocrinology, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Frederik A VerburgDepartment of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Hanneke M van SantenWilhelmina Children's Hospital and Princess Máxima Center, Utrecht, The Netherlands.ORCID 0000-0002-6773-6931

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At present, no European recommendations for the management of pediatric thyroid nodules and differentiated thyroid carcinoma (DTC) exist. Differences in clinical, molecular, and pathological characteristics between pediatric and adult DTC emphasize the need for specific recommendations for the pediatric population. An expert panel was instituted by the executive committee of the European Thyroid Association including an international community of experts from a variety of disciplines including pediatric and adult endocrinology, pathology, endocrine surgery, nuclear medicine, clinical genetics, and oncology. The 2015 American Thyroid Association Pediatric Guideline was used as framework for the present guideline. Areas of discordance were identified, and clinical questions were formulated. The expert panel members discussed the evidence and formulated recommendations based on the latest evidence and expert opinion. Children with a thyroid nodule or DTC require expert care in an experienced center. The present guideline provides guidance for healthcare professionals to make well-considered decisions together with patients and parents regarding diagnosis, treatment, and follow-up of pediatric thyroid nodules and DTC.

Indexed as

Europeanpediatricrecommendationthyroid cancerthyroid nodule

Identifiers

PMID36228315
PMCPMC9716393

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.