Evidence map›Paper›PMID 36228921›Full record

ArticleThe American journal of tropical medicine and hygiene2022

Malaria Resilience in South America: Epidemiology, Vector Biology, and Immunology Insights from the Amazonian International Center of Excellence in Malaria Research Network in Peru and Brazil.

Katherine Torres, Marcelo U Ferreira, Marcia C Castro, Ananias A Escalante, Jan E Conn, Elizabeth Villasis, Maisa da Silva Araujo, Gregorio Almeida, Priscila T Rodrigues, Rodrigo M Corder and 11 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Malaria control and the unexpected spread of diagnostic-resistantbioRxiv : the preprint server for biology · 2026
    Article
  3. Open forum infectious diseases · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Ecological change increases malaria risk in the Brazilian Amazon.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Katherine TorresInstitute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.
Marcelo U FerreiraDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Sao Paulo, Brazil.
Marcia C CastroDepartment of Global Health and Population, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
Ananias A EscalanteDepartment of Biology and Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, Pennsylvania.
Jan E ConnDepartment of Biomedical Sciences, School of Public Health, University at Albany, State University of New York, Albany, New York.
Elizabeth VillasisInstitute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.
Maisa da Silva AraujoInstituto de Pesquisas Rene Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
Gregorio AlmeidaInstituto de Pesquisas Rene Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
Priscila T RodriguesDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Sao Paulo, Brazil.
Rodrigo M CorderDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Sao Paulo, Brazil.
Anderson R J FernandesDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Sao Paulo, Brazil.
Priscila R CalilDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Sao Paulo, Brazil.
Winni A LadeiaDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Sao Paulo, Brazil.
Stefano S Garcia-CastilloLaboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru.
Joaquin GomezLaboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru.
Lis Ribeiro do Valle AntonelliInstituto de Pesquisas Rene Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
Ricardo T GazzinelliInstituto de Pesquisas Rene Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
Douglas T GolenbockDivision of Infectious Disease and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.
Alejandro Llanos-CuentasInstitute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.
Dionicia GamboaInstitute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.
Joseph M VinetzInstitute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Sugar-feeding behavior of the malaria vector Nyssorhynchus darlingi and development of effective attractive toxic sugar baits (ATSB) to increase intervention success in PeruU19AI089681 · NIAID · YALE UNIVERSITY · PI GAZZINELLI, RICARDO TOSTES · 2010 to 2023
$20.1M
Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
FIC NIH HHS D43 TW010540NCATS NIH HHS UL1 TR001863NIAID NIH HHS U19 AI089681
6 · The paper itself

Abstract

The 1990s saw the rapid reemergence of malaria in Amazonia, where it remains an important public health priority in South America. The Amazonian International Center of Excellence in Malaria Research (ICEMR) was designed to take a multidisciplinary approach toward identifying novel malaria control and elimination strategies. Based on geographically and epidemiologically distinct sites in the Northeastern Peruvian and Western Brazilian Amazon regions, synergistic projects integrate malaria epidemiology, vector biology, and immunology. The Amazonian ICEMR's overarching goal is to understand how human behavior and other sociodemographic features of human reservoirs of transmission-predominantly asymptomatically parasitemic people-interact with the major Amazonian malaria vector, Nyssorhynchus (formerly Anopheles) darlingi, and with human immune responses to maintain malaria resilience and continued endemicity in a hypoendemic setting. Here, we will review Amazonian ICEMR's achievements on the synergies among malaria epidemiology, Plasmodium-vector interactions, and immune response, and how those provide a roadmap for further research, and, most importantly, point toward how to achieve malaria control and elimination in the Americas.

Indexed as

AnophelesMalariaAnimalsBiologyBrazilHumansMosquito VectorsPeru

Identifiers

PMID36228921
PMCPMC9662219

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.