Evidence map›Paper›PMID 36229345›Full record

ReviewThe Lancet. Digital health2022

The promise of a model-based psychiatry: building computational models of mental ill health.

Tobias U Hauser, Vasilisa Skvortsova, Munmun De Choudhury, Nikolaos Koutsouleris

Abstract readReview
In one paragraph

Review in The Lancet. Digital health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Rapid and reliable computational markers of decision-making for predicting daily smoking behavior and smoking cessation treatment outcomes.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  14. How public involvement can improve the science of AI.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tobias U HauserMax Planck UCL Centre for Computational Psychiatry and Ageing Research, University College London, London, UK; Department of Psychiatry and Psychotherapy, Tübingen Center for Mental Health (TüCMH), Medical School and University Hospital, Eberhard Karls University of Tübingen, Tübingen, Germany; Wellcome Centre for Human Neuroimaging, University College London, London, UK. Electronic address: t.hauser@ucl.ac.uk.
Vasilisa SkvortsovaMax Planck UCL Centre for Computational Psychiatry and Ageing Research, University College London, London, UK; Wellcome Centre for Human Neuroimaging, University College London, London, UK.
Munmun De ChoudhurySchool of Interactive Computing, Georgia Institute of Technology, Atlanta GA, USA.
Nikolaos KoutsoulerisSection for Precision Psychiatry, Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University, Munich, Germany; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK; Max Planck Institute of Psychiatry, Munich, Germany.

Funding

ProNET: Psychosis-Risk Outcomes NetworkU01MH124639 · NIMH · YALE UNIVERSITY · PI CARRIE E BEARDEN, JOHN M KANE · 2020 to 2026
$81.2M
Leveraging Social Media Data and Machine Learning to Optimize Treatment Paradigms for Youth with SchizophreniaR01MH117172 · NIMH · GEORGIA INSTITUTE OF TECHNOLOGY · PI DE CHOUDHURY, MUNMUN · 2019 to 2022
$2.6M
NIMH NIH HHS R01 MH117172NIMH NIH HHS U01 MH124639Wellcome TrustWellcome Trust 203147/Z/16/ZWellcome Trust 211155/Z/18/Z
6 · The paper itself

Abstract

Computational models have great potential to revolutionise psychiatry research and clinical practice. These models are now used across multiple subfields, including computational psychiatry and precision psychiatry. Their goals vary from understanding mechanisms underlying disorders to deriving reliable classification and personalised predictions. Rapid growth of new tools and data sources (eg, digital data, gamification, and social media) requires an understanding of the constraints and advantages of different modelling approaches in psychiatry. In this Series paper, we take a critical look at the range of computational models that are used in psychiatry and evaluate their advantages and disadvantages for different purposes and data sources. We describe mechanism-driven and mechanism-agnostic computational models and discuss how interpretability of models is crucial for clinical translation. Based on these evaluations, we provide recommendations on how to build computational models that are clinically useful.

Indexed as

Mental DisordersPsychiatryComputer SimulationHumansMental Health

Identifiers

PMID36229345
PMCPMC9627546

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.