ReviewVirus genes2023
me53 encoded by Autographa californica multiple nucleopolyhedrovirus: from mechanism to function.
Review in Virus genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
me53, a highly conserved immediate early gene in all Lepidoptera baculoviruses, has been of great interest in recent years. Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is in the family Baculoviridae, genus Alphabaculovirus. The me53 gene of AcMNPV has been sequenced, and it was transcribed late after infection. The structure of ME53 protein and its roles in the infection of host cells were summarized and discussed, including that (1) the production of Budding Virus (BV); (2) nucleocapsid formation in the host nuclei; (3) ME53 forms a lesion on the cell membrane of AcMNPV-infected cells and co-locates with GP64 and the primary capsid protein VP39; (4) the nuclear translocation signal sequence of ME53 is essential for optimal baculovirus production. In this review, we focus on the emerging roles of ME53 by discussing novel mechanisms identified to mediate or interact by ME53, which provides an important reference for the effective transformation, utilization and improvement of the anti-insect activity of AcMNPV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.