Evidence map›Paper›PMID 36232007›Full record

ArticleInternational journal of environmental research and public health2022

Comparison of Concordance of Peptic Ulcer Disease, Non-Adenomatous Intestinal Polyp, and Gallstone Disease in Korean Monozygotic and Dizygotic Twins: A Cross-Sectional Study.

Hyo Geun Choi, So Young Kim, Hyun Lim, Joo-Hee Kim, Ji Hee Kim, Seong-Jin Cho, Eun Sook Nam, Kyueng-Whan Min, Ha Young Park, Nan Young Kim and 4 more

Open access · goldAbstract readTwin Study
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Hyo Geun ChoiDepartment of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.ORCID 0000-0003-1655-9549
So Young KimDepartment of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA University College of Medicine, Seongnam 13488, Korea.ORCID 0000-0002-7361-4930
Hyun LimDivision of Gastroenterology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.
Joo-Hee KimDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.
Ji Hee KimDepartment of Neurosurgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.ORCID 0000-0001-6937-8093
Seong-Jin ChoDepartment of Pathology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul 05355, Korea.
Eun Sook NamDepartment of Pathology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul 05355, Korea.
Kyueng-Whan MinDepartment of Pathology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri 11923, Korea.ORCID 0000-0002-4757-9211
Ha Young ParkDepartment of Pathology, Busan Paik Hospital, Inje University College of Medicine, Busan 47392, Korea.
Nan Young KimHallym Institute of Translational Genomics and Bioinformatics, Hallym University Medical Center, Anyang 14068, Korea.ORCID 0000-0001-9245-8657
Sangkyoon HongHallym Institute of Translational Genomics and Bioinformatics, Hallym University Medical Center, Anyang 14068, Korea.
Younghee ChoiDepartment of Pathology, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong 18450, Korea.
Ho Suk KangDivision of Gastroenterology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.
Mi Jung KwonDepartment of Pathology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.
Hallym University Sacred Heart Hospital · KRHallym University · KRHallym University Medical Center · KRCHA University Bundang Medical Center · KRHanyang University Guri Hospital · KRInje University Busan Paik Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiological studies have suggested the role of multiple genetic and environmental factors in the development of non-neoplastic gastrointestinal (GI) diseases; however, little information is available on these factors in the Korean population. Therefore, this cross-sectional study explored the effect of these factors by analyzing the concordance of several benign GI disorders in 525 monozygotic twins compared to that in 122 dizygotic twins aged >20 years from the Healthy Twin Study data of the Korean Genome and Epidemiology Study (2005-2014). Chi-square test, Wilcoxon rank-sum, and binomial and multinomial logistic regression models were used for statistical analysis. There was lack of concordance of gastric/duodenal ulcers and cholelithiasis/cholangitis between monozygotic twins compared to that in dizygotic twins, suggesting that environmental factors may mediate those concordant disease expressions in monozygotic twins. The concordance of intestinal polyps in monozygotic twins was 32% lower than that in dizygotic twins (

Indexed as

CholelithiasisPeptic UlcerCross-Sectional StudiesDiseases in TwinsHumansIntestinal PolypsRepublic of KoreaTwins, DizygoticTwins, Monozygoticcholangitischolelithiasisdizygotic twinsduodenal ulcerenvironmental factorgastric ulcergenetic influenceintestinal polypmonozygotic twins

Identifiers

PMID36232007
PMCPMC9566074
OpenAlexW4303696334

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.