Evidence map›Paper›PMID 36232447›Full record

ReviewInternational journal of molecular sciences2022

Waldenström Macroglobulinemia: Mechanisms of Disease Progression and Current Therapies.

Ava J Boutilier, Lina Huang, Sherine F Elsawa

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. The Direction of Modern Therapies in Waldenström Macroglobulinaemia.Journal of cellular and molecular medicine · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Signal Pathways in Cancer.International journal of molecular sciences · 2023
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ava J BoutilierDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH 03824, USA.ORCID 0000-0001-6307-9463
Lina HuangPhillips Exeter Academy, Exeter, NH 03833, USA.
Sherine F ElsawaDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH 03824, USA.ORCID 0000-0002-3917-3078
University of New Hampshire · USPhillips Exeter Academy · US

Funding

TLR-TRIF mediated induction of GLI3 modulates innate inflammatory responsesP20GM113131 · NIGMS · UNIVERSITY OF NEW HAMPSHIRE · PI Sean Stoddart Coleman Edington · 2017 to 2026
$22.8M
International Waldenstrom's Macroglobulinemia Foundation NALeukemia and Lymphoma Society NANIGMS NIH HHS P20 GM113131
6 · The paper itself

Abstract

Waldenström macroglobulinemia is an indolent, B-cell lymphoma without a known cure. The bone marrow microenvironment and cytokines both play key roles in Waldenström macroglobulinemia (WM) tumor progression. Only one FDA-approved drug exists for the treatment of WM, Ibrutinib, but treatment plans involve a variety of drugs and inhibitors. This review explores avenues of tumor progression and targeted drug therapy that have been investigated in WM and related B-cell lymphomas.

Indexed as

Lymphoma, B-CellWaldenstrom MacroglobulinemiaBone MarrowCytokinesDisease ProgressionHumansTumor MicroenvironmentCytokinesB-cell lymphomabone marrow microenvironmentdisease progressionnon-Hodgkin’stargeted therapyWaldenström macroglobulinemia

Identifiers

PMID36232447
PMCPMC9569492
OpenAlexW4296848631

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.