Evidence map›Paper›PMID 36232807›Full record

ArticleInternational journal of molecular sciences2022

Association of Common Variants in

Ting-Fong Lin, Chao-Liang Chou, Chu-Jui Hsieh, Yih-Jer Wu, Yi-Cheng Chen, Tzu-Wei Wu, Shu-Xin Lu, Yue-Li Juang, Li-Yu Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ting-Fong LinInstitute of Biomedical Sciences, MacKay Medical College, New Taipei City 252005, Taiwan.
Chao-Liang ChouDepartment of Medicine, MacKay Medical College, New Taipei City 252005, Taiwan.
Chu-Jui HsiehInstitute of Biomedical Sciences, MacKay Medical College, New Taipei City 252005, Taiwan.
Yih-Jer WuInstitute of Biomedical Sciences, MacKay Medical College, New Taipei City 252005, Taiwan.ORCID 0000-0002-5146-9234
Yi-Cheng ChenDepartment of Medicine, MacKay Medical College, New Taipei City 252005, Taiwan.ORCID 0000-0003-2443-7365
Tzu-Wei WuDepartment of Medicine, MacKay Medical College, New Taipei City 252005, Taiwan.
Shu-Xin LuDepartment of Neurology, MacKay Memorial Hospital, New Taipei City 251404, Taiwan.
Yue-Li JuangInstitute of Biomedical Sciences, MacKay Medical College, New Taipei City 252005, Taiwan.
Li-Yu WangDepartment of Medicine, MacKay Medical College, New Taipei City 252005, Taiwan.
Mackay Medical University · TWMackay Memorial Hospital · TW

Funding

MacKay Medical College, Taiwan 1081B15MacKay Medical College, Taiwan 1091B03Ministry of Science and Technology, Taiwan MOST 107-2314-B-715-003Ministry of Science and Technology, Taiwan MOST 108-2314-B-715-005-MY3The Wang Jhan-Yang Public Charitable Trust Fund WJY 2016-HR-01The Wang Jhan-Yang Public Charitable Trust Fund WJY 2017-HR-01
6 · The paper itself

Abstract

Reactive oxygen species impair the blood vessels, leading to the initiation of atherosclerosis, and migration and proliferation of vascular smooth muscle cells and neovascularization by endothelial cells of vasa vasorum are essential for atherosclerosis development. Obg-like ATPase 1 (OLA1), a negative regulator in cellular responses to oxidative stress, binds to breast cancer susceptibility gene 1 (BRCA1), which protects vascular endothelial and smooth muscle cells against reactive oxygen species. However, it is not known whether OLA1 is genetically correlated with atherosclerosis. Here, we conducted two independent population-based case-control studies to explore the effects of variants in

Indexed as

AtherosclerosisCarotid Intima-Media ThicknessAdenosine TriphosphatasesEndothelial CellsGenetic MarkersGTP-Binding ProteinsHumansReactive Oxygen SpeciesAdenosine TriphosphatasesGenetic MarkersGTP-Binding ProteinsOLA1 protein, humanReactive Oxygen SpeciesatherosclerosisBRCA1carotid intima–media thicknessgenetic association studyOLA1population-based studysingle nucleotide polymorphism

Identifiers

PMID36232807
PMCPMC9569939
OpenAlexW4297977722

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.