Evidence map›Paper›PMID 36233180›Full record

ArticleInternational journal of molecular sciences2022

Mitochondrial and Endoplasmic Reticulum Alterations in a Case of Amyotrophic Lateral Sclerosis Caused by TDP-43 A382T Mutation.

Giada Zanini, Valentina Selleri, Milena Nasi, Anna De Gaetano, Ilaria Martinelli, Giulia Gianferrari, Francesco Demetrio Lofaro, Federica Boraldi, Jessica Mandrioli, Marcello Pinti

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 17 citations in OpenAlex.

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  10. Proteomic Identification of ALDOA as a Pathogenic TDP-43 Interaction Partner in ALS.Degenerative neurological and neuromuscular disease · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Giada ZaniniDepartment of Life Sciences, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.
Valentina SelleriDepartment of Life Sciences, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.
Milena NasiDepartment of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0003-3079-8001
Anna De GaetanoDepartment of Life Sciences, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.
Ilaria MartinelliDepartment of Biomedical, Metabolic and Neurosciences, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.
Giulia GianferrariDepartment of Biomedical, Metabolic and Neurosciences, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.ORCID 0000-0002-4260-0915
Francesco Demetrio LofaroDepartment of Life Sciences, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.
Federica BoraldiDepartment of Life Sciences, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.ORCID 0000-0002-0277-9017
Jessica MandrioliDepartment of Biomedical, Metabolic and Neurosciences, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.ORCID 0000-0002-9244-9782
Marcello PintiDepartment of Life Sciences, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.ORCID 0000-0001-9118-1262
University of Modena and Reggio Emilia · IT

Funding

Italian Medicines Agency 2016-02364678
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis is the most common form of motor neuron disease. Mutations in

Indexed as

Amyotrophic Lateral SclerosisDNA-Binding ProteinsDNA, MitochondrialEndoplasmic ReticulumHumansMitochondriaMutationNucleotidyltransferasesProteomeRNA-Binding ProteinsDNA-Binding ProteinsDNA, MitochondrialNucleotidyltransferasesProteomeRNA-Binding Proteinsamyotrophic lateral sclerosismitochondriamtDNATDP-43

Identifiers

PMID36233180
PMCPMC9570187
OpenAlexW4303709833

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.