ReviewJournal of clinical medicine2022
Opportunities and Limits of Conventional IVF versus ICSI: It Is Time to Come off the Fence.
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Epigenetic, environmental, and sex-specific programming of long-term health in Assisted Reproductive Technologies-conceived offspring†.Biology of reproduction · 2026Review
- Use of virtual reality medical hypnosis for anxiolytic purposes during frozen embryo transfer: A prospective pilot study.PloS one · 2026Article
- Impact of oxidative stress on female reproductive parameters: an analysis of systemic and follicular biomarkers.JBRA assisted reproduction · 2025Article
- LOW FERTILIZATION: statistical definition and clinical relevance.Journal of assisted reproduction and genetics · 2025Article
- Non-human primates as a translational model for the study of male reproductive health.Nature reviews. Urology · 2025Review
- Assessing ambient air pollution's effects on birth outcomes: a Scottish IVF cohort study (2010 -2018).Environmental health : a global access science source · 2025Article
- Extracellular vesicles from different regions of the female reproductive tract promote spermatozoa motility and support capacitation.Scientific reports · 2025Article
- A compound heterozygous mutation in ZP1 and two novel heterozygous cis mutations in ZP3 causes infertility in women presenting with empty follicle syndrome.Journal of ovarian research · 2025Article
- In vitro fertilization induces reproductive changes in male mouse offspring and has multigenerational effects.JCI insight · 2025Article
- Informed consent in assisted reproductive technology: Implications for pediatric clinicians.Developmental medicine and child neurology · 2025Review
- Unveiling clinic variation in utilization of ICSI, PGT, and blastocyst transfer: a comprehensive study using the SART database (2014-2020).Journal of assisted reproduction and genetics · 2025Article
- Increased reproductive outcomes after optimized sperm preparation.Frontiers in cell and developmental biology · 2025Article
- Article
- Risk Factors for Prematurity and Congenital Malformations in Assisted Reproductive Technology Pregnancies-A Retrospective Study.Journal of clinical medicine · 2024Article
- Racial/ethnic disparity in severe maternal morbidity among women who conceived by in vitro fertilization.AJOG global reports · 2024Article
- Conventional IVF performs similarly in women with and without endometriosis.Journal of assisted reproduction and genetics · 2023Article
- Impact of intracytoplasmic sperm injection in women with non-male factor infertility: A systematic review and meta-analysis.Frontiers in reproductive health · 2022Review
- The Role of a Standardised Two-session Peri-transfer Acupuncture Protocol in Frozen Embryo Transfer for Women with Recurrent Implantation Failure: A Retrospective Cohort Study.Journal of human reproductive sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Conventional IVF (c-IVF) is one of the most practiced assisted reproductive technology (ART) approaches used worldwide. However, in the last years, the number of c-IVF procedures has dropped dramatically in favor of intracytoplasmic sperm injection (ICSI) in cases of non-male-related infertility. In this review, we have outlined advantages and disadvantages associated with c-IVF, highlighting the essential steps governing its success, its limitations, the methodology differences among laboratories and the technical progress. In addition, we have debated recent insights into fundamental questions, including indications regarding maternal age, decreased ovarian reserve, endometriosis, autoimmunity, single oocyte retrieval-cases as well as preimplantation genetic testing cycles. The "overuse" of ICSI procedures in several clinical situations of ART has been critically discussed. These insights will provide a framework for a better understanding of opportunities associated with human c-IVF and for best practice guidelines applicability in the reproductive medicine field.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.