Evidence mapPaperPMID 36235659Full record

ArticleNutrients2022

Effects of Maternal Gut Microbiota-Targeted Therapy on the Programming of Nonalcoholic Fatty Liver Disease in Dams and Fetuses, Related to a Prenatal High-Fat Diet.

Hong-Ren Yu, Jiunn-Ming Sheen, Chih-Yao Hou, I-Chun Lin, Li-Tung Huang, You-Lin Tain, Hsin-Hsin Cheng, Yun-Ju Lai, Yu-Ju Lin, Mao-Meng Tiao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
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  9. Heat-KilledNutrients · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Hong-Ren YuDepartment of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.ORCID 0000-0003-1242-8760
Jiunn-Ming SheenDepartment of Pediatrics, Chiayi Chang Gung Memorial Hospital, Puzi City 613, Taiwan.
Chih-Yao HouDepartment of Seafood Science, National Kaohsiung University of Science and Technology, Kaohsiung 811, Taiwan.ORCID 0000-0002-8007-6077
I-Chun LinDepartment of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.
Li-Tung HuangDepartment of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.ORCID 0000-0001-7403-288X
You-Lin TainDepartment of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.ORCID 0000-0002-7059-6407
Hsin-Hsin ChengDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung 833, Taiwan.
Yun-Ju LaiDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung 833, Taiwan.
Yu-Ju LinDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung 833, Taiwan.
Mao-Meng TiaoDepartment of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.
Ching-Chou TsaiDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung 833, Taiwan.ORCID 0000-0002-8302-1477
Chang Gung University · TWKaohsiung Chang Gung Memorial Hospital · TWChiayi Chang Gung Memorial Hospital · TWNational Kaohsiung Marine University · TW

Funding

Kaohsiung Chang Gung Memorial Hospital CMRPG8L1521, CMRPG8L1541 and CMRPG8M0391Ministry of Science and Technology, Taiwan MOST 111-2314-B-182-044
6 · The paper itself

Abstract

Metabolic disorders can start in utero. Maternal transmission of metabolic phenotypes may increase the risks of adverse metabolic outcomes, such as nonalcoholic fatty liver disease (NAFLD); effective intervention is essential to prevent this. The gut microbiome plays a crucial role in fat storage, energy metabolism, and NAFLD. We investigated the therapeutic use of probiotic

Indexed as

Gastrointestinal MicrobiomeNon-alcoholic Fatty Liver DiseaseAnimalsButyric AcidDiet, High-FatFatty Acids, VolatileFemaleFetusLiverObesityPlacentaPregnancyRatsRats, Sprague-DawleyButyric AcidFatty Acids, VolatilebutyrateDOHaDhigh-fat dietLactobacillus reuterinonalcoholic fatty liver diseaseprenatal

Identifiers

PMID36235659
PMCPMC9573493
OpenAlexW4297546697

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.