Evidence map›Paper›PMID 36235756›Full record

SynthesisNutrients2022

Effect of Personalized Nutrition on Dietary, Physical Activity, and Health Outcomes: A Systematic Review of Randomized Trials.

Sangeetha Shyam, Ke Xin Lee, Angeline Shu Wei Tan, Tien An Khoo, Shivani Harikrishnan, Shehzeen Alnoor Lalani, Amutha Ramadas

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
  2. Cost-Effectiveness of Personalised Nutrition in Adults With Overweight and Obesity: PREVENTOMICS Studies in Poland and the UK.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sangeetha ShyamCentre for Translational Research, IMU Institute for Research and Development (IRDI), International Medical University (IMU), Jalan Jalil Perkasa 19, Bukit Jalil, Kuala Lumpur 57000, Malaysia.ORCID 0000-0002-3340-1519
Ke Xin LeeJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.
Angeline Shu Wei TanJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.
Tien An KhooJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.
Shivani HarikrishnanWarwick Medical School, University of Warwick, Coventry CV4 7HL, UK.
Shehzeen Alnoor LalaniDalhousie Medicine DMNS, Dalhousie University, 5849 University Avenue, Halifax, NS B3H 4R2, Canada.ORCID 0000-0003-1091-6293
Amutha RamadasJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0002-8238-9659

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Personalized nutrition is an approach that tailors nutrition advice to individuals based on an individual's genetic information. Despite interest among scholars, the impact of this approach on lifestyle habits and health has not been adequately explored. Hence, a systematic review of randomized trials reporting on the effects of personalized nutrition on dietary, physical activity, and health outcomes was conducted. A systematic search of seven electronic databases and a manual search resulted in identifying nine relevant trials. Cochrane's Risk of Bias was used to determine the trials' methodological quality. Although the trials were of moderate to high quality, the findings did not show consistent benefits of personalized nutrition in improving dietary, behavioral, or health outcomes. There was also a lack of evidence from regions other than North America and Europe or among individuals with diseases, affecting the generalizability of the results. Furthermore, the complex relationship between genes, interventions, and outcomes may also have contributed to the scarcity of positive findings. We have suggested several areas for improvement for future trials regarding personalized nutrition.

Indexed as

DietExerciseHumansLife StyleNutritional StatusRandomized Controlled Trials as Topicnutrigeneticsnutrigenomicsnutrition interventionpersonalized nutrition

Identifiers

PMID36235756
PMCPMC9570623

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.