Evidence map›Paper›PMID 36235778›Full record

SynthesisNutrients2022

Efficacy and Safety of Polaprezinc-Based Therapy versus the Standard Triple Therapy for

Abdelrahman Mahmoud, Mohamed Abuelazm, Ali Ashraf Salah Ahmed, Hassan Abdalshafy, Basel Abdelazeem, James Robert Brašić

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07275827 (Comparative Study Evaluating Safety and Effectiveness of), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07275827 phase3not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection

TypeinterventionalSponsorTanta UniversityRan2026 to 2026Enrolled88ConditionsHELICOBACTER PYLORI INFECTIONSArmszinc sulfate, Vonoprazan + amoxicillin + clarithromycin, proton pump inhibitor + amoxicillin
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. A review for non-antibiotic treatment ofFrontiers in microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Abdelrahman MahmoudFaculty of Medicine, Minia University, Minia 61519, Egypt.
Mohamed AbuelazmFaculty of Medicine, Tanta University, Tanta 31527, Egypt.
Ali Ashraf Salah AhmedFaculty of Medicine, Minia University, Minia 61519, Egypt.ORCID 0000-0003-3870-5148
Hassan AbdalshafyFaculty of Medicine, Cairo University, Cairo 11562, Egypt.
Basel AbdelazeemDepartment of Internal Medicine, McLaren Health Care, Flint, MI 48532, USA.ORCID 0000-0002-2919-6196
James Robert BrašićSection of High Resolution Brain Positron Emission Tomography Imaging, Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-3948-4853
Minia University · EGCairo University · EGJohns Hopkins University · USMcLaren Health Care · USTanta University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CarnosineHelicobacter InfectionsOrganometallic CompoundsZinc CompoundsAmoxicillinAnti-Bacterial AgentsClarithromycinDrug Therapy, CombinationHelicobacter pyloriHumansProton Pump InhibitorsRandomized Controlled Trials as TopicAmoxicillinAnti-Bacterial AgentsCarnosineClarithromycinOrganometallic CompoundspolaprezincProton Pump InhibitorsZinc Compoundsalternative interventioncarnosineconfidence intervalflow chartgastrointestinal disorderplaceboprotocolrandomtreatmentzinc

Identifiers

PMID36235778
PMCPMC9573391
OpenAlexW4303962114

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.