Evidence map›Paper›PMID 36237197›Full record

ArticleFrontiers in endocrinology2022

Prevalence of nocturnal hypoglycemia in free-living conditions in adults with type 1 diabetes: What is the impact of daily physical activity?

Joséphine Molveau, Rémi Rabasa-Lhoret, Étienne Myette-Côté, Virginie Messier, Corinne Suppère, Kathryn J Potter, Elsa Heyman, Sémah Tagougui

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Joséphine MolveauInstitut de recherches cliniques de Montréal, Montréal, QC, Canada.
Rémi Rabasa-LhoretInstitut de recherches cliniques de Montréal, Montréal, QC, Canada.
Étienne Myette-CôtéInstitut de recherches cliniques de Montréal, Montréal, QC, Canada.
Virginie MessierInstitut de recherches cliniques de Montréal, Montréal, QC, Canada.
Corinne SuppèreInstitut de recherches cliniques de Montréal, Montréal, QC, Canada.
Kathryn J PotterInstitut de recherches cliniques de Montréal, Montréal, QC, Canada.
Elsa HeymanUniv. Lille, Univ. Artois, Univ. Littoral Côte d'Opale, ULR 7369 - URePSSS - Unité de Recherche Pluridisciplinaire Sport Santé Société, Lille, France.
Sémah TagouguiInstitut de recherches cliniques de Montréal, Montréal, QC, Canada.
Montreal Clinical Research Institute · CAUnité de Recherche Pluridisciplinaire Sport, Santé, Société · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Studies investigating strategies to limit the risk of nocturnal hypoglycemia associated with physical activity (PA) are scarce and have been conducted in standardized, controlled conditions in people with type 1 diabetes (T1D). This study sought to investigate the effect of daily PA level on nocturnal glucose management in free-living conditions while taking into consideration reported mitigation strategies to limit the risk of nocturnal hyoglycemia in people with T1D. Methods: Data from 25 adults (10 males, 15 females, HbA Results: Only 44% of participants reported applying a carbohydrate- or insulin-based strategy to limit the risk of nocturnal hypoglycemia on ACT day. Nocturnal hypoglycemia occurrences were comparable on ACT night versus on L-ACT night. Additional post-meal carbohydrate intake was higher on evenings following ACT (27.7 ± 15.6 g, ACT vs. 19.5 ± 11.0 g, L-ACT; P=0.045), but was frequently associated with an insulin bolus (70% of participants). Nocturnal hypoglycemia the night following ACT occurred mostly in people who administrated an additional insulin bolus before midnight (3 out of 5 participants with nocturnal hypoglycemia). Conclusions: Although people with T1D seem to be aware of the increased risk of nocturnal hypoglycemia associated with PA, the risk associated with additional insulin boluses may not be as clear. Most participants did not report using compensation strategies to reduce the risk of PA related late-onset hypoglycemia which may be because they did not consider habitual PA as something requiring treatment adjustments.

Indexed as

Diabetes Mellitus, Type 1HypoglycemiaAdultBlood GlucoseBlood Glucose Self-MonitoringExerciseFemaleGlucoseHumansHypoglycemic AgentsInsulinMaleMiddle AgedPrevalenceSocial ConditionsYoung AdultBlood GlucoseGlucoseHypoglycemic AgentsInsulinaccelerometercontinous glucose monitoringhypoglycemianocturnal glucose controlphysical activity leveltype 1 diabetes

Identifiers

PMID36237197
PMCPMC9551602
OpenAlexW4297294420

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.