Evidence map›Paper›PMID 36246601›Full record

ArticleFrontiers in genetics2022

Development of a prognostic prediction model based on a combined multi-omics analysis of head and neck squamous cell carcinoma cell pyroptosis-related genes.

Bin Chen, Yuanbo Luo, Xueran Kang, Yuxing Sun, Chenyan Jiang, Bin Yi, Xiaojun Yan, Yisheng Chen, Runjie Shi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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  5. The High-Affinity IL-2 Receptor Affects White Matter Damage after Cerebral Ischemia by Regulating CD8 + T Lymphocyte Differentiation.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Bin ChenDepartment of Otorhinolaryngology Head and Neck Surgery, Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Yuanbo LuoDepartment of Otorhinolaryngology Head and Neck Surgery, Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Xueran KangDepartment of Otorhinolaryngology Head and Neck Surgery, Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Yuxing SunDepartment of Otorhinolaryngology Head and Neck Surgery, Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Chenyan JiangDepartment of Otorhinolaryngology Head and Neck Surgery, Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Bin YiDepartment of Otorhinolaryngology Head and Neck Surgery, Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Xiaojun YanDepartment of Otorhinolaryngology Head and Neck Surgery, Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Yisheng ChenDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Runjie ShiDepartment of Otorhinolaryngology Head and Neck Surgery, Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Shanghai Jiao Tong University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to understand the prognosis of patients with head and neck squamous cell carcinoma (HNSCC) and to develop and validate a prognostic model for HNSCC based on pyroptosis-associated genes (PAGs) in nasopharyngeal carcinoma. The Cancer Genome Atlas database was used to identify differentially expressed PAGs. These genes were analyzed using the Kyoto Encyclopedia of Genes and Genomes functional annotation analyses and Gene Ontology analyses. The NLR family pyrin domain containing 1 (

Indexed as

head and neck squamous cell carcinoma (HNSCC)immune infiltrationnasopharyngeal carcinoma (NPC)prognostic modelpyroptosis

Identifiers

PMID36246601
PMCPMC9557126
OpenAlexW4298001988

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.