Evidence map›Paper›PMID 36249398›Full record

ArticleACS omega2022

Design of Anti-infectious Agents from Lawsone in a Three-Component Reaction with Aldehydes and Isocyanides.

Christina L Koumpoura, Michel Nguyen, Christian Bijani, Laure Vendier, Elena G Salina, Silvia Buroni, Giulia Degiacomi, Sandrine Cojean, Philippe M Loiseau, Françoise Benoit-Vical and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Christina L KoumpouraLaboratoire de Chimie de Coordination du CNRS-UPR8241, Inserm ERL 1289 Team "New antiplasmodial molecules and pharmacological approaches", 205 route de Narbonne, BP 44099, Toulouse Cedex 31077, France.ORCID https://orcid.org/0000-0001-6819-7266
Michel NguyenLaboratoire de Chimie de Coordination du CNRS-UPR8241, Inserm ERL 1289 Team "New antiplasmodial molecules and pharmacological approaches", 205 route de Narbonne, BP 44099, Toulouse Cedex 31077, France.
Christian BijaniLaboratoire de Chimie de Coordination du CNRS-UPR8241, Inserm ERL 1289 Team "New antiplasmodial molecules and pharmacological approaches", 205 route de Narbonne, BP 44099, Toulouse Cedex 31077, France.
Laure VendierLaboratoire de Chimie de Coordination du CNRS-UPR8241, Inserm ERL 1289 Team "New antiplasmodial molecules and pharmacological approaches", 205 route de Narbonne, BP 44099, Toulouse Cedex 31077, France.
Elena G SalinaBach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russia.
Silvia BuroniDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia 27100, Italy.
Giulia DegiacomiDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia 27100, Italy.
Sandrine CojeanAntiparasite Chemotherapy, UMR 8076 CNRS BioCIS, Faculty of Pharmacy, University Paris-Saclay, Châtenay-Malabry 92290, France.
Philippe M LoiseauAntiparasite Chemotherapy, UMR 8076 CNRS BioCIS, Faculty of Pharmacy, University Paris-Saclay, Châtenay-Malabry 92290, France.
Françoise Benoit-VicalLaboratoire de Chimie de Coordination du CNRS-UPR8241, Inserm ERL 1289 Team "New antiplasmodial molecules and pharmacological approaches", 205 route de Narbonne, BP 44099, Toulouse Cedex 31077, France.
Alfonso T García-SosaDepartment of Molecular Technology, Institute of Chemistry, University of Tartu, Ravila 14a, Tartu 50411, Estonia.ORCID https://orcid.org/0000-0003-0542-4446
Anne RobertLaboratoire de Chimie de Coordination du CNRS-UPR8241, Inserm ERL 1289 Team "New antiplasmodial molecules and pharmacological approaches", 205 route de Narbonne, BP 44099, Toulouse Cedex 31077, France.ORCID https://orcid.org/0000-0002-9092-6776
Michel BaltasLaboratoire de Chimie de Coordination du CNRS-UPR8241, Inserm ERL 1289 Team "New antiplasmodial molecules and pharmacological approaches", 205 route de Narbonne, BP 44099, Toulouse Cedex 31077, France.ORCID https://orcid.org/0000-0002-8785-7095

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first effective synthetic approach to naphthofuroquinones via a reaction involving lawsone, various aldehydes, and three isocyanides under microwave irradiation afforded derivatives in moderate to good yields. In addition, for less-reactive aldehydes, two naphtho-enaminodione quinones were obtained for the first time, as result of condensation between lawsone and isocyanides. X-ray structure determination for

Identifiers

PMID36249398
PMCPMC9558256

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.